Understanding chronic fatigue in outpatient clinics

Patients with Chronic Fatigue Complaints for Whom a Consultation Including Diagnostics Do Not Reveal a Somatic Diagnosis Atthe Internal Medicine Outpatient Clinic

Observational Flevoziekenhuis · NCT06775262

This study is trying to see how well doctors can diagnose chronic fatigue in outpatient clinics and to understand what patients feel when they leave without a diagnosis.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorFlevoziekenhuis Academic / other
Locations1 site (Almere Stad, Flevoland)
Trial IDNCT06775262 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of diagnostic procedures for chronic fatigue in an internal medicine outpatient clinic and explores patient experiences when no diagnosis is made. It employs a mixed-methods approach, combining a retrospective analysis of electronic health records to assess the diagnostic yield of fatigue consultations with qualitative interviews to gather insights from patients who leave without a diagnosis. The aim is to enhance understanding and management of chronic fatigue, which affects a significant portion of the population. By integrating quantitative and qualitative data, the study seeks to provide a comprehensive view of the diagnostic process and patient experiences.

Who should consider this trial

Good fit: Ideal candidates are adults at the internal medicine outpatient clinic referred for fatigue who did not receive a somatic diagnosis.

Not a fit: Patients under 18 years of age or those who do not speak Dutch fluently may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic strategies and better management of chronic fatigue for patients.

How similar studies have performed: While studies on chronic fatigue exist, this mixed-methods approach focusing on both diagnostic efficacy and patient experiences is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Cohort 1:

Inclusion Criteria:

* Patients under 18 years of age;
* Patients lost to follow-up.

Exclusion Criteria:

* Patients at the internal medicine outpatient clinic with a referral for fatigue e.c.i.
* Patients who visited the clinic after the 1st of April 2022.

Cohort 2:

Inclusion criteria

* Patients at the internal medicine outpatient clinic with a referral for fatigue e.c.i. whose consultation did not bring about a somatic diagnosis

Exclusion criteria:

* Patients under 18 years of age;
* Patients that do not speak Dutch fluently

Where this trial is running

Almere Stad, Flevoland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Fatigue SymptomFatigueFatigue Syndrome, ChronicQualitative studyQuantative studyDiagnostic efficacyInternal medicineInterviews
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.