Understanding cancer risks from firefighter occupational exposures
Effect of Occupational Exposures on Cancer Pathophysiology Among Firefighters
This study looks at whether exposure to certain chemicals and metals increases cancer risk in current and former firefighters compared to a small group of non-firefighters.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Vincere Cancer Center Academic / other |
| Locations | 1 site (Scottsdale, Arizona) |
| Trial ID | NCT06173843 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the impact of occupational exposures, particularly PFAS and heavy metals, on cancer risk among firefighters. Participants include current and former firefighters who are part of Vincere's First Responder Cancer Screening Program. The study will involve collecting blood, urine, and tissue samples to analyze the effects of these exposures. A small group of non-firefighters will also be included for comparison purposes.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 and older who are currently or have previously worked as firefighters.
Not a fit: Patients who are not firefighters or those who do not meet the eligibility criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide critical insights into cancer risks associated with firefighting, potentially leading to improved safety measures and health outcomes for firefighters.
How similar studies have performed: While studies on occupational exposures and cancer risks exist, this specific focus on firefighters and PFAS is relatively novel and may provide new insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older; any gender * Currently (or previously) employed as a firefighter, full-time or part-time, participating in Vincere's First Responder Cancer Screening Program * Willing to provide a blood, urine, and/or tissue sample * Able to provide informed consent to participate in the study (A small group of non-firefighters will be enrolled to act as a comparison group)
Where this trial is running
Scottsdale, Arizona
- Vincere Cancer Center — Scottsdale, Arizona, United States (Recruiting)
Study contacts
- Study coordinator: Christine Lau, MD
- Email: drlau@vincerecancer.com
- Phone: 480-306-5390
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.