Understanding cancer risks from firefighter occupational exposures
Official title: Effect of Occupational Exposures on Cancer Pathophysiology Among Firefighters
Run by Vincere Cancer Center · NCT06173843 · Data updated 2026-11-12
This study looks at whether exposure to certain chemicals and metals increases cancer risk in current and former firefighters compared to a small group of non-firefighters.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Vincere Cancer Center Academic / other |
| Locations | 1 site (Scottsdale, Arizona) |
| Status | Recruiting |
| Started | December 6, 2023 |
| Main results expected | December 31, 2028 |
| Study ends | December 31, 2029 |
| Registry record updated | November 14, 2024 |
| Trial ID | NCT06173843 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 18 and older who are currently or have previously worked as firefighters.
✕Probably not a fit
Patients who are not firefighters or those who do not meet the eligibility criteria may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the impact of occupational exposures, particularly PFAS and heavy metals, on cancer risk among firefighters. Participants include current and former firefighters who are part of Vincere's First Responder Cancer Screening Program. The study will involve collecting blood, urine, and tissue samples to analyze the effects of these exposures. A small group of non-firefighters will also be included for comparison purposes.
Why it matters
Potential benefit: If successful, this study could provide critical insights into cancer risks associated with firefighting, potentially leading to improved safety measures and health outcomes for firefighters.
How similar studies have gone: While studies on occupational exposures and cancer risks exist, this specific focus on firefighters and PFAS is relatively novel and may provide new insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older; any gender * Currently (or previously) employed as a firefighter, full-time or part-time, participating in Vincere's First Responder Cancer Screening Program * Willing to provide a blood, urine, and/or tissue sample * Able to provide informed consent to participate in the study (A small group of non-firefighters will be enrolled to act as a comparison group)
Where it's running
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Vincere Cancer Center
Scottsdale, Arizona, United States Recruiting
Study contacts
- Study coordinator: Christine Lau, MD
- Email: drlau@vincerecancer.com
- Phone: 480-306-5390
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Collection of biospecimens for cancer research
This study is collecting blood, urine, and tissue samples from people to help researchers find better ways to screen for and treat cancer.
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Early cancer detection tests for firefighters
This study is testing new blood and urine tests to see if they can help detect cancer early in firefighters who are at higher risk due to their job.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.