Early cancer detection tests for firefighters
Official title: Multi-Cancer Early Detection (MCED) of Firefighters
Run by Vincere Cancer Center · NCT05780957 · Data updated 2026-11-12
This study is testing new blood and urine tests to see if they can help detect cancer early in firefighters who are at higher risk due to their job.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Vincere Cancer Center Academic / other |
| Locations | 1 site (Scottsdale, Arizona) |
| Status | Recruiting |
| Started | March 21, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2030 |
| Registry record updated | November 5, 2025 |
| Trial ID | NCT05780957 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are firefighters aged 18 and older who are currently employed and able to provide blood and urine samples.
✕Probably not a fit
Patients with a personal history of cancer in the last 5 years, except for non-melanoma skin cancer, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the effectiveness of new blood and urine tests designed for the early detection of cancer specifically in firefighters. Participants will be recruited from Vincere's First Responder Cancer Screening Program and will provide blood and urine samples for analysis. The study focuses on understanding how well these tests can identify cancer at an early stage among individuals who are at higher risk due to their occupation. The findings could help improve cancer screening protocols for firefighters.
Why it matters
Potential benefit: If successful, this study could lead to earlier cancer detection in firefighters, potentially improving treatment outcomes.
How similar studies have gone: While there have been studies on cancer detection in various populations, this specific approach targeting firefighters is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * Currently employed as a firefighter, full-time or part-time * Taking part in Vincere's First Responder Cancer Screening Program * Able to donate blood and urine sample * Able to provide informed consent to participate in the study Exclusion Criteria: * Deemed medically unfit for sample donation * Personal history of cancer in the last 5 years (with the exception of non-melanoma skin cancer)
Where it's running
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Vincere Cancer Center
Scottsdale, Arizona, United States Recruiting
Study contacts
- Principal investigator: Vershalee Shukla, MD — Vincere Cancer Center
- Study coordinator: Christine Lau, MD
- Email: drlau@vincerecancer.com
- Phone: 480-306-5390
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Understanding cancer risks from firefighter occupational exposures
This study looks at whether exposure to certain chemicals and metals increases cancer risk in current and former firefighters compared to a small group of non-firefighters.
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Collection of biospecimens for cancer research
This study is collecting blood, urine, and tissue samples from people to help researchers find better ways to screen for and treat cancer.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.