Understanding cancer risks from environmental contaminants during pregnancy

DREAM: Discovering Cancer Risks From Environmental Contaminants And Maternal/Child Health

Observational University of California, San Francisco · NCT05746169

This study is trying to see how exposure to chemicals in everyday products and pollution during pregnancy might affect cancer risks for moms and their kids.

Quick facts

Study typeObservational
Enrollment10000 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of California, San Francisco Academic / other
Locations3 sites (Berkeley, California and 2 other locations)
Trial IDNCT05746169 on ClinicalTrials.gov

What this trial studies

The DREAM Cohort is a longitudinal observational study aimed at exploring the relationship between environmental chemical exposures and cancer risks in pregnant women and their children. It focuses on two main types of exposures: chemicals from consumer products and environmental pollutants in air and water. Data will be collected through health questionnaires and biospecimen samples starting in the second trimester of pregnancy and continuing until the child is four years old. The study also includes a Cohort Ambassador Program to engage participants in shaping research priorities.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women over the age of 18 who speak English or Spanish.

Not a fit: Patients who are under 18 years old or expecting multiples will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide critical insights into how environmental factors during pregnancy influence cancer risk in children.

How similar studies have performed: Other studies have shown success in linking environmental exposures to health outcomes, making this approach both relevant and promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pregnant women, over the age of 18 years.
* English or Spanish-speaking.
* Children born of participants enrolled during pregnancy will be enrolled in the DREAM cohort.
* Inclusion criterion for the DREAM Cohort Ambassador Program is limited to research participants in the DREAM Cohort.

Exclusion Criteria:

* Women under the age of 18.
* Women expecting the birth of multiples (twins, triplets, etc.).

Where this trial is running

Berkeley, California and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerCancer RiskEnvironmental Cancer RiskMaternal-Child Cancer RiskEnvironmental Contaminants
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.