Understanding brain activity related to speech in neurological diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research focuses on how brain activity affects speech perception and production in individuals with neurological disorders like Parkinson's disease and dystonia. The study will utilize a novel experimental approach and various analytic techniques to investigate the role of neural activity in cortical-basal ganglia circuits during speech production. Participants will be individuals scheduled for deep brain stimulation surgery, allowing researchers to collect electrophysiological data to better understand these processes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subjects scheduled for DBS implantation, as determined by the clinical multidisciplinary movement disorders board with definitive diagnosis of Parkinson's disease, essential tremor or dystonia.
2. Subjects able to provide informed consent and comply with task instructions.
3. Subjects 18-85 years old

Exclusion Criteria:

1. Subjects with reported hearing loss.
2. Non-English-speaking subjects

Where it's running

• Massachusetts General Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Study coordinator: Mark Richardson, MD, PhD
• Email: mark.richardson@mgh.harvard.edu
• Phone: 617-726-8849

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.