Understanding brain activity related to fear and anxiety

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the brain mechanisms that contribute to fear and anxiety disorders, such as PTSD and GAD. Participants will undergo brain activity monitoring, heart rate measurement, and skin perspiration assessment while completing various tasks, including those in a virtual reality environment designed to provoke fear. The study will involve individuals who have had neurostimulation electrode placement, allowing researchers to gather data on how these interventions affect emotional responses. The goal is to enhance understanding of anxiety disorders and potentially improve treatment strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age or older
* Has undergone acute depth or chronic responsive neurostimulation (RNS) electrode placement
* Willing to provide informed consent and participate in the study
* Ability to read and write English fluently

Exclusion Criteria:

* Unwilling to provide informed consent
* Has not undergone acute depth or chronic responsive neurostimulation (RNS) electrode placement
* Pregnant women
* Participants with active psychosis
* Participants with suicidal ideation
* Participants with substance abuse issues

Where it's running

• University of California Los Angeles
  Los Angeles, California, United States Recruiting
• Duke University Health System
  Durham, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Nanthia Suthana, PhD — Duke Health
• Study coordinator: Aaron Halvorsen, PhD
• Email: suthanalab@duke.edu
• Phone: 9196812577

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.