Understanding brain activity related to cognitive issues in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to investigate the brain activity associated with cognitive impairment in patients with Parkinson's disease. By utilizing neural recordings from corticostriatal structures during deep brain stimulation surgery, researchers will measure the neural activity that underlies nonmotor symptoms of the disease. The approach involves direct observation of brain function in a clinical setting, providing valuable insights into the cognitive aspects of Parkinson's disease.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
* Planned clinical electrode trajectory that contacts caudate
* Age greater than or equal to 40
* Diagnosis of Parkinson's disease
* Able to participate in intraoperative testing
* English speaking

Exclusion criteria:

* Age less than 40
* Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
* Movement disorder other than Parkinson's disease

Where it's running

• Vanderbilt University Medical Center
  Nashville, Tennessee, United States Recruiting

Study contacts

• Principal investigator: Sarah Bick, MD — Vanderbilt University Medical Center
• Study coordinator: Lucas Chang, BA
• Email: lucas.m.chang@vumc.org
• Phone: 615-421-3046

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.