Understanding biomarkers in patients undergoing high-risk surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the perioperative biomarker responses in patients undergoing high-risk surgeries, such as cardiac, colorectal, vascular, and lung procedures. By collecting blood samples and clinical data from 4,819 patients, the study seeks to identify biomarkers that can predict postoperative complications and improve risk stratification. The goal is to develop a predictive model that can guide treatment decisions and enhance patient outcomes following surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Cardiac surgery (isolated coronary artery bypass grafting or combined with single valve surgery, isolated single valve surgery)
* Gastrointestinal surgery (colorectal, pancreatic, gastric surgery).
* Vascular surgery (open and endovascular aortic surgery, peripheral vascular surgery)
* Lung surgery (pneumonectomy,(bi)(sleeve)lobectomy or segmentectomy)

Exclusion Criteria:

* Age \< 18 years
* Pregnancy
* Emergent surgery
* No informed consent

Where it's running

• Amphia Hospital
  Breda, North Brabant, Netherlands Recruiting
• St Antonius Hospital
  Nieuwegein, Utrecht, Netherlands Recruiting

Study contacts

• Study coordinator: Peter Noordzij
• Email: p.noordzij@antoniusziekenhuis.nl
• Phone: 0031883203000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.