Understanding and treating Polycystic Ovary Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects clinical data and serum samples from women with polycystic ovary syndrome (PCOS) to analyze various factors such as body measurements, skin conditions, diet, and hormonal levels. Using statistical software and experimental techniques, the study aims to identify new biomarkers and explore the mechanisms behind PCOS. The goal is to create a comprehensive clinical research database that supports personalized medicine approaches for PCOS management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female aged 18- 45;

Exclusion Criteria:

* Female patients younger than 18 years old or older than 45 years old;
* Ovulatory disorders caused by premature ovarian failure, pituitary amenorrhea, hypothalamic amenorrhea, and thyroid dysfunction;
* Congenital adrenal hyperplasia, reservoir Hin syndrome, hyperprolactinemia, adrenal tumors and other diseases that cause hyperandrogenism;
* Abnormal liver or renal function((≥ 3 times of the upper limit of normal range)
* Type 1 diabetes, single gene mutation diabetes, or pancreatic damage Diabetes or other secondary diabetes caused by diabetes;
* History of malignant tumors;
* Severe infection, severe anemia, neutropenia and other systemic chronic diseases;
* Undergo total hysterectomy or ovarian adnexectomy;
* Mental illness, dementia or other cognitive behavioral problems;
* Use hypoglycemic drugs that may affect insulin resistance and androgen levels in the last 3 months, including thiazolidinediones, metformin, SGLT-2, and acarbose and GLP-1RA and other drugs;
* Use letrozole, clomiphene, oral contraceptives, glucocorticoids, gonadotropins, gonadotropin-releasing hormone agonists, anti-androgens (spironolactone, Cyproterone acetate, flutamide, etc.) and other drugs for the treatment of PCOS.

Where it's running

• Department of Endocrinology, Shanghai Tenth People's Hospital
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Manna Zhang, Dr
• Email: mannazhang@126.com
• Phone: 86-21-66301004

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Precision acupuncture and lifestyle for PCOS

  This trial tests whether a precision acupuncture approach combined with a personalized lifestyle plan helps improve insulin resistance in people with PCOS compared with conventional acupuncture and standard lifestyle changes.

  Recruiting Peking University Third Hospital · Beijing, Beijing Municipality and 1 other locations · NCT07809503

• Orlistat for metabolic and hormonal features in women with PCOS

  This trial tests whether adding orlistat to lifestyle advice helps improve metabolic and hormonal aspects in women with PCOS compared to lifestyle advice alone.

  Recruiting Khyber Medical University Peshawar · Abbottābād, Khyber Pakhtunkhwa · NCT07747909

• Physical activity program for women with PCOS and fatty pancreas plus subclinical hypothyroidism

  A program of exercise is being tested to see if it helps women with PCOS who also have fatty pancreas and subclinical hypothyroidism, compared to usual care.

  Recruiting Cairo University · Giza · NCT07591246

• Glucose monitoring in women with polycystic ovary syndrome

  This project will use continuous glucose monitors to see if daily glucose patterns differ among adult women with different PCOS phenotypes.

  Recruiting Centre Hospitalier Universitaire, Amiens · Salouël · NCT07483723

• Adding regular exercise to a low‑calorie diet and metformin for women with PCOS and asthma

  This study will test whether adding regular treadmill walking to a low‑calorie diet and daily metformin helps women who have both PCOS and asthma.

  Recruiting Cairo University · Giza, Dokki · NCT07446985

• Identifying insulin-resistant PCOS with LMNA-related lipodystrophy in young women

  We’re testing whether women with a genetic insulin resistance and lipodystrophy differ from women with PCOS by age and BMI matching.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07412028

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.