Ultrasound treatment for insulin resistance in women with central obesity
Official title: Effect of Ultrasound Cavitation on Insulin Resistance in Patients with Central Obesity in Female
Run by Cairo University · NCT06729203 · Data updated 2026-11-12
This study tests if combining ultrasound treatments with exercise and a low-calorie diet can help women aged 25 to 40 with central obesity improve their insulin resistance and body shape.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 25 Years to 40 Years |
| Sex | Women only |
| Enrollment | 52 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza, Giza Governorate) |
| Status | Recruiting |
| Started | December 1, 2024 |
| Main results expected | February 1, 2025 |
| Study ends | December 1, 2025 |
| Registry record updated | December 11, 2024 |
| Trial ID | NCT06729203 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are sedentary women aged 25 to 40 with a BMI between 30 and 35 kg/m2 and diagnosed with insulin resistance.
✕Probably not a fit
Patients with diabetes, metabolic disorders, or those on weight-loss medications are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of ultrasound cavitation combined with aerobic exercise and a low-calorie diet on insulin resistance and body contouring in women aged 25 to 40 with central obesity. Participants will undergo ultrasound treatments while following a structured exercise and dietary program. The primary focus is to assess changes in insulin resistance, measured by HOMA-IR, as well as improvements in body composition. The study aims to provide clearer evidence on the efficacy of ultrasound cavitation in managing obesity-related insulin resistance.
Why it matters
Potential benefit: If successful, this approach could offer a non-invasive method to improve insulin sensitivity and aid in weight management for women with central obesity.
How similar studies have gone: While there is limited evidence on the effects of ultrasound cavitation on insulin resistance, similar studies have shown promise in body contouring and metabolic improvements.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female subjects with central obesity. * Female participants aged between 25 to 40 years. * Body Mass Index (BMI) ranged from 30 to 35 kg/m2 as high BMI indicates more obesity and central obesity. * Waist circumference greater than 88 cm, indicative of abdominal obesity. * Diagnosed with insulin resistance (HOMA-IR \> 2.9). * Sedentary lifestyle, defined as engaging in less than 150 minutes of moderate-intensity physical activity per week. * Willingness to provide informed consent and comply with study procedures. Exclusion Criteria: * • Subjects diagnosed with DM (HbA1c more than 6.5%). * History of metabolic disorders such as type 1 diabetes or thyroid disorders. * Subjects with BMI less than 30 kg/m2. * Subjects diagnosed with heart disease, liver as well as kidney diseases. * Subjects who take oral contraceptives. * Subjects with gestational Diabetes. * Pregnant or breastfeeding women were excluded from the study. * Use of weight-loss medications or supplements within the past six months. * Previous surgical procedures for weight loss or body contouring. * Contraindications to ultrasound therapy (e.g., metal implants in the abdomen, active skin infections). * Participation in another clinical trial within the last three months.
Where it's running
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Cairo University
Giza, Giza Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Aya Saeed Shazly, Master degree
- Email: aya_saeedpt@yahoo.com
- Phone: 00201096841660
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.