Ultrasound-guided scalp block to improve blood pressure, heart rate stability and pain after craniotomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, interventional study compares an ultrasound-guided scalp block plus general anesthesia to standard surgical site infiltration with local anesthetic during elective supratentorial craniotomy. Primary questions are whether the scalp block smooths intraoperative hemodynamic fluctuations and decreases postoperative pain and opioid consumption within 24 hours. Participants receive general anesthesia and are assigned to receive either the scalp nerve block or the infiltration technique, with continuous monitoring of heart rate, blood pressure, and other vitals during surgery. Ultrasound guidance is used to improve accuracy and safety of the scalp block. The trial aims to determine if targeted regional anesthesia can improve perioperative stability and analgesia, potentially reducing systemic analgesic requirements.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-64 years.
* ASA (American Society of Anesthesiologists) physical status I or II.
* Patients scheduled for elective supratentorial craniotomy.
* BMI of 18 to 30 kg/m².
* GCS score of 9 to 15.

Exclusion Criteria:

* Patient with instable blood pressure and heart rate.
* Known allergy or hypersensitivity to local anesthetics.
* Coagulation disorders or current anticoagulant therapy.
* Infection at the injection site or systemic infection.
* Patients with open skull defects.

Where it's running

• Bangladesh Medical University
  Dhaka, Bangladesh Recruiting

Study contacts

• Study coordinator: Kazi Mahzabin Arin, MD
• Email: kazimahzabinarin@bsmmu.edu.bd
• Phone: +8801754057689

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing dexmedetomidine and bupivacaine for pain management after brain surgery

  This study is testing if adding dexmedetomidine to bupivacaine can help reduce pain better after brain surgery compared to using bupivacaine alone.

  Recruiting Ain Shams University · Cairo · NCT06993922

• Examining how Guselkumab affects immune cells in scalp psoriasis

  This study is testing how the medication Guselkumab affects immune cells in people with moderate to severe scalp psoriasis to see how it helps their condition.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT05858632

• Scalp care for hair transplant patients using a test shampoo plus basic shampoo

  In this study, 120 Chinese men who have had hair transplants will try a special shampoo plus a basic shampoo to see if it improves scalp health and seborrheic dermatitis compared with a basic shampoo alone.

  Recruiting ChinaNorm · Shanghai · NCT07641686

• Veregen 10% ointment for actinic keratosis on the face and bald scalp

  This trial will test whether applying Veregen 10% ointment clears mild-to-moderate actinic keratoses on the face or bald scalp better than a placebo in adults.

  Recruiting Phase 3 Aresus Pharma GmbH · Strausberg · NCT07137819

• What causes a sensitive scalp?

  This study will try to find biological differences in scalp tissue and microbes between adult women who do and do not have a sensitive scalp by taking a small scalp biopsy, microbiota samples, and questionnaires.

  Recruiting University Hospital, Brest · Brest · NCT07156422

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.