Ultrasound-guided pulsed radiofrequency treatment for knee osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of ultrasound-guided pulsed radiofrequency treatment on the genicular nerves in patients suffering from chronic knee osteoarthritis. Participants will undergo a double diagnostic genicular nerve block followed by either real or sham pulsed radiofrequency treatment. The primary focus is to assess improvements in pain, function, and reduction in analgesic use over time. Given the increasing prevalence of knee osteoarthritis, this approach seeks to provide an alternative to conventional treatments and surgical options.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Chronic knee pain with pain intensity of at least 4 out 10 on the VAS on most or all days for more than 3 months
* Patients of either sex with primary osteoarthritis of one or both knees fulfilling diagnostic criteria for osteoarthritis knee laid down by American College of Rheumatology.
* Patients also had to have a Kellgren-Lawrence (radiologic criterion) score of at least 2
* Pain resistant to conventional therapy including NSAIDs, opioids, muscle relaxants, oral steroids, physical therapy, and intra-articular injection therapy.

Exclusion Criteria:

* The patients with secondary osteoarthritis of knees
* Associated systemic arthropathies, e.g. rheumatoid arthritis and gout
* Previous radiofrequency ablation treatment for similar symptoms.
* Intra-articular knee corticosteroid or hyaluronic acid injection in the past 3 months.
* Active systemic or local infections at the site of proposed needle and electrode placement.
* Coagulopathy or other bleeding disorder
* Cognitive deficit.
* Unstable medical or psychiatric illness.
* Previous knee joint replacement surgery
* Patients missing two or more appointments consecutively were excluded from the study

Where it's running

• Son Llatzer University Hospital
  Palma, Balear Islands, Spain Recruiting

Study contacts

• Principal investigator: Javier Mata, MD — Son Llatzer University Hospital
• Study coordinator: Javier Mata, MD
• Email: jmata@hsll.es
• Phone: 0034871201233

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.