Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Ultrasound-guided nerve block to help with pain after groin cancer surgery

Official title: Evaluation of Ultrasound Guided- Chemical Rectus Sheath Block for Chronic Pain After Abdominal Midline Incision in Cancer Surgeries: A Prospective Randomized Controlled Study

Run by National Cancer Institute, Egypt · NCT07855380 · Data updated 2026-11-12

This study tests whether an ultrasound-guided transversalis fascia plane block can reduce pain around the time of surgery for adults with cancer undergoing inguinal lymph node dissection.

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Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment90 (estimated)
SponsorNational Cancer Institute, Egypt
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedMay 1, 2026
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedOctober 2, 2026
Trial IDNCT07855380 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–65 with cancer requiring inguinal lymph node dissection, ASA I–II, BMI 20–40 kg/m2.

Probably not a fit

Patients with contraindications to regional anesthesia, coagulopathy, infection at the puncture site, or allergies to study medications may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study explores the analgesic effect of a saline transversalis fascia plane block performed under ultrasound guidance in cancer patients undergoing inguinal lymph node dissection. The procedure targets nerves in the abdominal wall to potentially improve perioperative pain control. Eligible participants are adults 18–65 with ASA I–II status and BMI 20–40 kg/m2, undergoing the specified cancer surgery. Block technique involves saline as the injectate and is performed under ultrasound visualization to identify the relevant muscle layers. The trial aims to determine if this regional anesthesia approach can provide better analgesia and potentially reduce opioid needs during the perioperative period.

Why it matters

Potential benefit: If successful, patients may experience better perioperative pain relief and reduced need for systemic analgesics after inguinal lymph node dissection.

How similar studies have gone: Previous reports describe the use of transversalis fascia plane blocks in various abdominopelvic surgeries; data on cancer surgery analgesia is evolving but shows potential benefit.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* American Society of Anesthesiologists (ASA) class I and II.
* Age ≥ 18 and ≤ 65 Years.
* Cancer patients for inguinal lymph node dissection.
* Body mass index (BMI): \> 20 kg/m2 and \< 40 kg/m2.

Exclusion Criteria:

* Patient refusal.
* Local infection at the puncture site.
* Coagulopathies with platelet count below 50,000 or an INR\>1.6.
* Unstable cardiovascular disease.
* History of psychiatric and cognitive disorders.
* Patients allergic to medication used.

Where it's running

  • Cairo University
    Cairo, Egypt
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.