TrueBlue mobile app for tracking depression and anxiety during pregnancy and after birth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This early-phase interventional study will recruit adults in the perinatal period (between 12 weeks of pregnancy and up to 12 weeks postpartum) across NHS sites in Nottinghamshire to use the TrueBlue app over a 12-week period. An initial pilot of up to 12 participants will check recruitment, usability, and any device-related adverse events before expanding to a total target of 125 participants over 14 months. Participants will complete two app tasks per week that involve reading or speaking while the app records face and voice data, and they will complete four validated questionnaires (PHQ-9, EPDS, GAD-7, TEPS) every two weeks. Adverse events will be actively monitored at weeks 6 and 12 and reviewed for possible links to app use.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- 18 years or older

* Fluent in spoken and written English
* Has capacity to provide consent
* At least 12 weeks pregnant or less than 12 weeks postpartum
* Access to internet connectivity
* Access to a compatible smart phone device (for up to 10 participants, where needed through not having a personal device, this access may be provided through the study team).
* Has a current GP within Nottinghamshire

Exclusion Criteria:

* ● Current clinically diagnosed psychiatric disorder other than depression

  * Previous history of a clinically diagnosed psychiatric disorder, other than depression and generalised anxiety disorder (including previous Psychosis, Bipolar Disorder, Personality Disorder, Substance Abuse Disorders, Eating Disorders)
  * Clinical diagnosis of an Autistic Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Parkinson's Disease or other current Neurological Disorder.

Where it's running

• Nottinghamshire Healthcare NHS Foundation Trust
  Nottingham, United Kingdom Recruiting
• Nottingham University Hospitals NHS Trust
  Nottingham, Nottinghamshire, United Kingdom Not yet recruiting

Study contacts

• Principal investigator: Neil Nixon, MBBS — School of Medicine, University of Nottingham and Nottinghamshire Healthcare NHS Trust
• Study coordinator: John Michaelis, BSc
• Email: john@blueskeye.com
• Phone: 01689 856664

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Two-week smartphone program to boost reward response in people with anhedonia

  This trial tests whether three brief daily smartphone audio exercises teaching positive imagery, savoring, gratitude, and related skills can reduce anhedonia and psychological distress in German-speaking adults with elevated anhedonia and depression.

  Recruiting Philipps University Marburg · Marburg, Hesse · NCT07155941

• Mindful Smartphone Use: A Mindfulness-Based Program for Teens with Sleep and Mood Challenges

  This study tests Mindwire, a mindfulness-based program, to see if it helps teens with problematic phone use who also have depression or anxiety.

  Recruiting Brown University · Providence, Rhode Island · NCT07892807

• Tele-based wellbeing centres for women's mental health in Bangladesh

  A randomized trial tests whether tele-counselling for depression and anxiety in Bangladeshi women is as effective as in-person counselling.

  Recruiting at 2 sites International Centre for Diarrhoeal Disease Research, Bangladesh · Chāndpur, Matlab Dakshin and 1 other locations · NCT07890896

• HBOT to see if it helps cognition and well‑being in first responders with prior brain injury

  This study tests whether 40 hyperbaric oxygen therapy sessions can improve thinking skills and post-concussion symptoms in current or former first responders with a history of brain injury.

  Recruiting Phase 2 Summit Hyperbarics and Wellness · Boise, Idaho · NCT07852728

• Focused ultrasound for mood and anxiety disorders

  This study tests whether repeated low-intensity focused ultrasound using the ATTN201 device can help people with subsyndromal to moderate depression, anxiety, or OCD.

  Recruiting Attune Neurosciences Inc · San Francisco, California and 1 other locations · NCT07851038

• An Ultra-Brief ICBT Intervention with Personal Feedback for Depression and Anxiety

  This trial tests whether adding personalized feedback about a person’s recent healthy actions to the Things You Do ultra-brief online CBT program helps adults with depression and anxiety do more healthy activities and feel better.

  Recruiting University of Regina · Regina, Saskatchewan · NCT07806864

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.