Treatment to improve fertilization in infertility cases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research focuses on enhancing fertilization rates in patients experiencing infertility due to fertilization failure. The study involves preparing sperm using a membrane permeabilizing agent and injecting it into oocytes, which are then activated to promote embryo development. The efficacy of this gamete treatment will be assessed by monitoring fertilization success and embryo development over a standard culture period. The goal is to provide a viable option for patients who have previously faced fertilization challenges.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with complete fertilization failure with standard IVF or failure with one prior ICSI treatment cycle

Exclusion Criteria:

* not meeting inclusion criteria
* IVF without ICSI

Where it's running

• Center fo Reproductive Medicine
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Gianpiero Palermo, MD, MPH — Weill Medical College of Cornell University
• Study coordinator: Rodriq Stubbs, NP
• Email: res2011@med.cornell.edu
• Phone: 646-962-3276

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Ultra-Long GnRH-a Pretreatment Before Frozen Embryo Transfer for Deep Infiltrating Endometriosis

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• Endometrial Waves and Pregnancy in FET Cycles with Hormone Therapy

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  Recruiting Mỹ Đức Hospital · Ho Chi Minh City · NCT07675213

• Environmental and lifestyle factors linked to ART success in infertility patients

  This study follows 5,000 infertile men and women to see how environmental exposures and lifestyle relate to the success of assisted reproductive technology.

  Recruiting The Third Xiangya Hospital of Central South University · Changsha, Hunan · NCT07641387

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.