Treatment of Helicobacter Pylori Infection in Children with Nitazoxanide
Study of Novel Triple Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori in Children
This study is testing a new combination treatment for Helicobacter pylori infections in children to see if it works better than current options.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta) |
| Trial ID | NCT04415983 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of a novel triple therapy regimen using Nitazoxanide (NTZ) combined with Clarithromycin and Metronidazole, along with a proton pump inhibitor, to treat Helicobacter pylori infections in children. The approach aims to provide a new therapeutic option for this common infection, which can lead to significant gastrointestinal issues if left untreated. The study is designed as a Phase 3 interventional trial, focusing on children who test positive for Helicobacter pylori.
Who should consider this trial
Good fit: Ideal candidates for this study are children who have tested positive for Helicobacter pylori infection.
Not a fit: Patients who have previously undergone treatment for Helicobacter pylori will not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a more effective and safer option for eradicating Helicobacter pylori in children.
How similar studies have performed: Other studies have explored treatments for Helicobacter pylori, but the specific use of Nitazoxanide in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Positive helicobacter infection. Exclusion Criteria: * Previous treatment for H. Pylori.
Where this trial is running
Tanta
- Sherief Abd-Elsalam — Tanta, Egypt (Recruiting)
Study contacts
- Principal investigator: Rasha Gamal, Ass. Prof. — Pediatrics department - Tanta University
- Study coordinator: Sherief Abd-Elsalam, ass. prof.
- Email: sheriefabdelsalam@yahoo.com
- Phone: 00201147773440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.