Treatment for peri-implantitis using implantoplasty
Surgical Peri-implantitis Treatment With and Without Implantoplasty
This study tests if adding implantoplasty to standard treatment helps people with peri-implantitis heal better than just the standard treatment alone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 35 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | University of Oslo Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 2 sites (Oslo, Oslo and 1 other locations) |
| Trial ID | NCT04052373 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of implantoplasty in treating peri-implantitis through a controlled, randomized, split-mouth design. Participants will undergo open flap debridement, with some receiving additional implantoplasty to assess its impact on treatment outcomes. The study aims to compare the results of these two approaches in managing peri-implant conditions. It is conducted at a single center, ensuring a controlled environment for data collection and analysis.
Who should consider this trial
Good fit: Ideal candidates are individuals with peri-implantitis affecting at least two implants with significant surface exposure and loss.
Not a fit: Patients with a history of certain medical treatments or conditions, such as chemotherapy or bisphosphonate use, may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could improve outcomes for patients suffering from peri-implantitis, potentially leading to better implant longevity and oral health.
How similar studies have performed: While there is ongoing research in this area, the specific combination of treatments being tested in this trial is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Peri-implantitis (according to 2018 criteria) on minimum 2 implants of similar surface and defect type * Competent to give consent * Exposed, modified implant surface with loss \>2mm Exclusion Criteria: * Previous radiotherapy to the jaws, current use of chemotherapy, systemic long-term corticosteroid treatment * Present or past use of bisphosphonate treatment • Pregnant or nursing subjects * Patients classified as \> class II according to ASA classification * Implant unavailable for implantoplasty treatment * Inhability to comprehend and respond to the quality of life questionnaire * Examiners/operators deem original placement of implant (angle, position) suboptimal and considered to play a major role in development of peri-implantitis * History of peri-implantitis surgery prior to 6 months of screening
Where this trial is running
Oslo, Oslo and 1 other locations
- Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo — Oslo, Oslo, Norway (Recruiting)
- Institute of Clinical Dentistry, University of Oslo, Norway — Oslo, Norway (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.