Treatment for peri-implantitis using implantoplasty
Official title: Surgical Peri-implantitis Treatment With and Without Implantoplasty
Run by University of Oslo · NCT04052373 · Data updated 2026-11-12
This study tests if adding implantoplasty to standard treatment helps people with peri-implantitis heal better than just the standard treatment alone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 35 (estimated) |
| Sponsor | University of Oslo Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 2 sites (Oslo, Oslo and 1 other locations) |
| Status | Recruiting |
| Started | October 15, 2019 |
| Main results expected | June 15, 2027 |
| Study ends | June 15, 2027 |
| Registry record updated | April 29, 2026 |
| Trial ID | NCT04052373 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with peri-implantitis affecting at least two implants with significant surface exposure and loss.
✕Probably not a fit
Patients with a history of certain medical treatments or conditions, such as chemotherapy or bisphosphonate use, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of implantoplasty in treating peri-implantitis through a controlled, randomized, split-mouth design. Participants will undergo open flap debridement, with some receiving additional implantoplasty to assess its impact on treatment outcomes. The study aims to compare the results of these two approaches in managing peri-implant conditions. It is conducted at a single center, ensuring a controlled environment for data collection and analysis.
Why it matters
Potential benefit: If successful, this treatment could improve outcomes for patients suffering from peri-implantitis, potentially leading to better implant longevity and oral health.
How similar studies have gone: While there is ongoing research in this area, the specific combination of treatments being tested in this trial is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Peri-implantitis (according to 2018 criteria) on minimum 2 implants of similar surface and defect type * Competent to give consent * Exposed, modified implant surface with loss \>2mm Exclusion Criteria: * Previous radiotherapy to the jaws, current use of chemotherapy, systemic long-term corticosteroid treatment * Present or past use of bisphosphonate treatment • Pregnant or nursing subjects * Patients classified as \> class II according to ASA classification * Implant unavailable for implantoplasty treatment * Inhability to comprehend and respond to the quality of life questionnaire * Examiners/operators deem original placement of implant (angle, position) suboptimal and considered to play a major role in development of peri-implantitis * History of peri-implantitis surgery prior to 6 months of screening
Where it's running
-
Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo
Oslo, Oslo, Norway Recruiting -
Institute of Clinical Dentistry, University of Oslo, Norway
Oslo, Norway Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.