Treatment for narrowing of vertebral arteries using drug-eluting stents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of a drug-eluting stent system for patients with atherosclerotic vertebral artery stenosis, which can lead to ischemic strokes. It is a prospective, multi-center, open-access, single-arm trial where participants will be monitored for clinical outcomes at 30 days, 6 months, and 12 months post-procedure, with annual follow-ups for up to three years. The study focuses on assessing the long-term efficacy of the stent in reducing the risk of stroke recurrence and improving neurological outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years old, gender is not limited;
2. Patients with medically prescribed rapamycin drug-eluting vertebral artery stent systems;
3. Patients and family members fully understand the trial's purpose, voluntarily participate in the trial and sign the informed consent form.

Exclusion Criteria:

1. Unable to receive dual antiplatelet therapy due to known disease, or severe coagulation abnormalities, severe infections that are not controlled, severe systemic disease, uncontrollable hypertension, and contraindicated for surgery;
2. With an aneurysm that cannot be treated earlier or simultaneously or is not suitable for surgery;
3. Gastrointestinal disease with active bleeding;
4. Previous myocardial infarction or large-scale cerebral infarction within 2 weeks;
5. Known contraindications to heparin, rapamycin, anesthesia, and contrast agents;
6. Life expectancy less than 12 months;
7. the investigator judged patients to be unsuitable for participation in this study.

Where it's running

• Nanfang Hospital of Southern Medical University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Principal investigator: Zhong Ji, PHD — Nanfang Hospital, Southern Medical University
• Study coordinator: Zhong Ji, PHD
• Email: jizhong22@hotmail.com
• Phone: 020-62787664

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Preventing another ischemic stroke with a smart bracelet and app

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  Recruiting Affiliated Hospital of Nantong University · Nantong, Jiangsu · NCT07825311

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.