Treatment for lung fibrosis caused by cancer therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of Bevasizumab, a VEGF inhibitor, in treating acute pulmonary fibrosis that occurs as a result of radiation and chemotherapy in cancer patients. Participants will be randomly assigned to receive either Bevasizumab combined with Dexamethasone or Dexamethasone alone. The study will assess various biomarkers and imaging results at multiple time points to evaluate the treatment's impact. The target sample size is 30 patients, focusing on those diagnosed with treatment-induced pulmonary fibrosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* clinical diagnosed cancer treatment-induced acute pulmonary fibrosis

Exclusion Criteria:

* chronic pulmonary fibrosis and infection-induced pulmonary fibrosis
* active bleeding
* uncontrolled high blood pressure
* unstable systemic disease
* prior exposure to VEGF inhibitor

Where it's running

• Qingdao Central Hospital
  Qingdao, Shandong, China Recruiting

Study contacts

• Principal investigator: youxin ji, md — Qingdao Central Hospital
• Study coordinator: youxin ji, md
• Email: ji6677@gmail.com
• Phone: 86532-68665078

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Home monitoring for patients with pulmonary fibrosis

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• Understanding genetic and environmental factors in pulmonary fibrosis

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  Recruiting Royal College of Surgeons, Ireland · Dublin · NCT06702228

• Identifying biomarkers for progressive pulmonary fibrosis in lung disease patients

  This study is trying to find early signs that can help predict if adults with certain lung diseases will develop progressive pulmonary fibrosis over the next five years.

  Recruiting Amsterdam UMC, location VUmc · Amsterdam, North Holland · NCT06644144

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.