Treatment approaches for HPV-related lesions in women

Predictors of Recurrence After Treatment (Surgery Plus Vaccination) of HPV-related Disease of the Female Genital Tract

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · NCT05938192

This study looks at whether getting vaccinated after surgery for HPV-related lesions can help reduce the chances of women developing cervical dysplasia or cancer later on.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexFemale
SponsorFondazione IRCCS Istituto Nazionale dei Tumori, Milano (other)
Locations1 site (Milan, Lombardy)
Trial IDNCT05938192 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the risk of recurrence in women with HPV-related lesions who have undergone surgical treatment, with or without subsequent HPV vaccination. It focuses on understanding how these interventions impact the likelihood of developing cervical dysplasia and cervical cancer. The study will involve monitoring patients over time to assess outcomes related to their HPV status and treatment history.

Who should consider this trial

Good fit: Ideal candidates for this study are women diagnosed with HPV-related diseases, particularly those with cervical dysplasia.

Not a fit: Patients who have withdrawn consent or do not have HPV-related conditions will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for women at risk of cervical cancer due to HPV-related lesions.

How similar studies have performed: Other studies have shown success in managing HPV-related lesions, but this specific approach combining surgery and vaccination is less commonly tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with HPV related disease

Exclusion Criteria:

* consent withdrawal

Where this trial is running

Milan, Lombardy

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: HPV, Cervical Cancer, Cervix Lesion, Vagina Disease, hpv

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.