Treatment approaches for HPV-related lesions in women
Official title: Predictors of Recurrence After Treatment (Surgery Plus Vaccination) of HPV-related Disease of the Female Genital Tract
Run by Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · NCT05938192 · Data updated 2026-11-12
This study looks at whether getting vaccinated after surgery for HPV-related lesions can help reduce the chances of women developing cervical dysplasia or cancer later on.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 200 (estimated) |
| Sponsor | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano Academic / other |
| Locations | 1 site (Milan, Lombardy) |
| Status | Recruiting |
| Started | July 15, 2020 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2028 |
| Registry record updated | May 9, 2025 |
| Trial ID | NCT05938192 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women diagnosed with HPV-related diseases, particularly those with cervical dysplasia.
✕Probably not a fit
Patients who have withdrawn consent or do not have HPV-related conditions will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the risk of recurrence in women with HPV-related lesions who have undergone surgical treatment, with or without subsequent HPV vaccination. It focuses on understanding how these interventions impact the likelihood of developing cervical dysplasia and cervical cancer. The study will involve monitoring patients over time to assess outcomes related to their HPV status and treatment history.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for women at risk of cervical cancer due to HPV-related lesions.
How similar studies have gone: Other studies have shown success in managing HPV-related lesions, but this specific approach combining surgery and vaccination is less commonly tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with HPV related disease Exclusion Criteria: * consent withdrawal
Where it's running
-
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
Milan, Lombardy, Italy Recruiting
Study contacts
- Principal investigator: Giorgio Bogani — Giorgio Bogani
- Study coordinator: Giorgio Bogani, md
- Email: giorgiobogani@yahoo.it
- Phone: 917-275-6975
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.