Clinical trial Recruiting at 1 site Observational Ages 18 and up Women only

Treatment approaches for HPV-related lesions in women

Official title: Predictors of Recurrence After Treatment (Surgery Plus Vaccination) of HPV-related Disease of the Female Genital Tract

Run by Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · NCT05938192 · Data updated 2026-11-12

This study looks at whether getting vaccinated after surgery for HPV-related lesions can help reduce the chances of women developing cervical dysplasia or cancer later on.

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment200 (estimated)
SponsorFondazione IRCCS Istituto Nazionale dei Tumori, Milano
Academic / other
Locations1 site (Milan, Lombardy)
StatusRecruiting
StartedJuly 15, 2020
Main results expectedDecember 30, 2026
Study endsDecember 30, 2028
Registry record updatedMay 9, 2025
Trial IDNCT05938192 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women diagnosed with HPV-related diseases, particularly those with cervical dysplasia.

Probably not a fit

Patients who have withdrawn consent or do not have HPV-related conditions will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the risk of recurrence in women with HPV-related lesions who have undergone surgical treatment, with or without subsequent HPV vaccination. It focuses on understanding how these interventions impact the likelihood of developing cervical dysplasia and cervical cancer. The study will involve monitoring patients over time to assess outcomes related to their HPV status and treatment history.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for women at risk of cervical cancer due to HPV-related lesions.

How similar studies have gone: Other studies have shown success in managing HPV-related lesions, but this specific approach combining surgery and vaccination is less commonly tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with HPV related disease

Exclusion Criteria:

* consent withdrawal

Where it's running

  • Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
    Milan, Lombardy, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.