Treadmill walking plus diet for women with psoriasis and PCOS.
Official title: Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?
Run by Cairo University · NCT07289399 · Data updated 2026-11-12
This will test whether adding 40-minute treadmill walks three times a week to a low-calorie diet and daily metformin helps women who have both psoriasis and PCOS.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 35 Years to 45 Years |
| Sex | Women only |
| Enrollment | 40 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza, Dokki) |
| Status | Recruiting |
| Started | October 10, 2025 |
| Main results expected | May 15, 2026 |
| Study ends | May 15, 2026 |
| Registry record updated | December 17, 2025 |
| Trial ID | NCT07289399 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult women with class I obesity who have chronic plaque psoriasis and diagnosed PCOS and who can safely perform moderate treadmill exercise and take metformin.
✕Probably not a fit
Women with significant cardiac, liver, respiratory, or vascular disease, or those who do not have both psoriasis and PCOS or are not obese, are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Forty women with chronic plaque psoriasis and PCOS will be assigned to one of two 12-week groups at Cairo University. The intervention group will perform 40 minutes of treadmill walking three times per week in addition to following a low-calorie diet and taking daily metformin, while the comparison group will follow the low-calorie diet and daily metformin alone. Outcomes will be tracked over 12 weeks to observe changes in clinical status and related metabolic measures. Key safety exclusions include significant cardiac, liver, respiratory, or vascular disease.
Why it matters
Potential benefit: If successful, adding regular treadmill walking could improve skin symptoms, weight, and metabolic or reproductive features in these women.
How similar studies have gone: Diet and exercise interventions have shown benefits for obesity and PCOS and exercise may help psoriasis, but direct trials combining treadmill walking with diet and metformin in women who have both conditions are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * obese (class I) women * chronic plaque psoriasis * polyscytic ovarian syndrome Exclusion Criteria: * cardiac dysfucntions * liver diseases * repsiratory disease * vascular diseases
Where it's running
-
Cairo University
Giza, Dokki, Egypt Recruiting
Study contacts
- Principal investigator: Ali MA Ismail, lecturer — Cairo University
- Study coordinator: Ali MA Ismail, lecturer
- Email: ali.mohamed@pt.cu.edu.eg
- Phone: 01005154209
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.