Clinical trial Recruiting at 1 site Interventional Ages 16 to 60 Men only

Transjugular and Transfemoral Embolization for Varicocele

Official title: Combined Role of Transjugular and Transfemoral Embolization in the Management of Varicocele.

Run by Sohag University · NCT07764900 · Data updated 2026-11-12

This procedure comparison study tests two embolization approaches for varicocele to see which method works best for men with enlarged veins around the testicle.

Quick facts

Study typeInterventional
Ages16 Years to 60 Years
SexMen only
Enrollment30 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag, Sohag Governorate)
StatusRecruiting
StartedApril 10, 2026
Main results expectedMarch 10, 2027
Study endsMay 10, 2027
Registry record updatedAugust 14, 2026
Trial IDNCT07764900 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are male patients aged 16–60 with clinically palpable Grade II/III varicocele or subclinical varicocele with abnormal semen parameters, including those with recurrent varicocele after prior surgery.

Probably not a fit

Patients without varicocele-related symptoms, those with contraindications to endovascular procedures, or those with allergies to iodinated contrast may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective interventional study will compare transjugular and transfemoral embolization using NBCA to treat varicocele in up to 30 male participants aged 16–60. Patient venous anatomy will determine the approach, and each participant will be followed at one and three months after the procedure to assess effectiveness, symptom changes, and safety. Outcomes include treatment success, improvement in symptoms, and any procedure-related complications. The study is sponsored by Sohag University and conducted at its Faculty of Medicine in Sohag, Egypt.

Why it matters

Potential benefit: If successful, the approach could provide effective treatment for varicocele with symptom relief and potential fertility benefits.

How similar studies have gone: Previous embolization studies for varicocele have shown promise with NBCA, but direct head-to-head comparison of transjugular versus transfemoral approaches in this setting is limited, making this study relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 1\. Male patients aged 16-60 years. 2. Clinically palpable varicocele (Grade II or III) or subclinical varicocele associated with abnormal semen parameters.

  3\. Recurrent varicocele following previous surgical treatment. 4. Presence of scrotal pain, testicular atrophy, or infertility attributed to varicocele.

  5\. Willingness to participate in the study and provide written informed consent.

Exclusion Criteria:

\- 1. Secondary varicocele due to a retroperitoneal mass or renal vein obstruction.

2\. Known allergy to iodinated contrast media. 3. Coagulation disorders or contraindications to endovascular procedures.

Where it's running

  • Sohag University - Faculty of Medicine
    Sohag, Sohag Governorate, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.