Transjugular and Transfemoral Embolization for Varicocele
Official title: Combined Role of Transjugular and Transfemoral Embolization in the Management of Varicocele.
Run by Sohag University · NCT07764900 · Data updated 2026-11-12
This procedure comparison study tests two embolization approaches for varicocele to see which method works best for men with enlarged veins around the testicle.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 16 Years to 60 Years |
| Sex | Men only |
| Enrollment | 30 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag, Sohag Governorate) |
| Status | Recruiting |
| Started | April 10, 2026 |
| Main results expected | March 10, 2027 |
| Study ends | May 10, 2027 |
| Registry record updated | August 14, 2026 |
| Trial ID | NCT07764900 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are male patients aged 16–60 with clinically palpable Grade II/III varicocele or subclinical varicocele with abnormal semen parameters, including those with recurrent varicocele after prior surgery.
✕Probably not a fit
Patients without varicocele-related symptoms, those with contraindications to endovascular procedures, or those with allergies to iodinated contrast may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective interventional study will compare transjugular and transfemoral embolization using NBCA to treat varicocele in up to 30 male participants aged 16–60. Patient venous anatomy will determine the approach, and each participant will be followed at one and three months after the procedure to assess effectiveness, symptom changes, and safety. Outcomes include treatment success, improvement in symptoms, and any procedure-related complications. The study is sponsored by Sohag University and conducted at its Faculty of Medicine in Sohag, Egypt.
Why it matters
Potential benefit: If successful, the approach could provide effective treatment for varicocele with symptom relief and potential fertility benefits.
How similar studies have gone: Previous embolization studies for varicocele have shown promise with NBCA, but direct head-to-head comparison of transjugular versus transfemoral approaches in this setting is limited, making this study relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. Male patients aged 16-60 years. 2. Clinically palpable varicocele (Grade II or III) or subclinical varicocele associated with abnormal semen parameters. 3\. Recurrent varicocele following previous surgical treatment. 4. Presence of scrotal pain, testicular atrophy, or infertility attributed to varicocele. 5\. Willingness to participate in the study and provide written informed consent. Exclusion Criteria: \- 1. Secondary varicocele due to a retroperitoneal mass or renal vein obstruction. 2\. Known allergy to iodinated contrast media. 3. Coagulation disorders or contraindications to endovascular procedures.
Where it's running
-
Sohag University - Faculty of Medicine
Sohag, Sohag Governorate, Egypt Recruiting
Study contacts
- Study coordinator: arsanious Maher adib, MBBCh
- Email: arsanuoesmaher@gmail.com
- Phone: +201287522810
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.