Clinical trial Recruiting at 1 site Observational Ages 18 and up

Is geographic mismatch linked to short-term major heart problems after long drug-eluting stent placement?

Official title: Geographic Mismatch as A Predictor of Short-Term Major Adverse Cardiovascular Events Following Long Coronary Stent Implantation; A Prospective Cohort Study

Run by Sohag University · NCT07890181 · Data updated 2026-11-12

This study checks whether geographic mismatch can predict short-term major adverse cardiovascular events after a long drug-eluting stent is placed in the coronary arteries.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment650 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedMay 1, 2027
Study endsMay 1, 2027
Registry record updatedOctober 22, 2026
Trial IDNCT07890181 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older undergoing PCI with successful DES implantation of at least 38 mm in length and discharged after the procedure.

Probably not a fit

Patients receiving bare-metal stents, those with cardiogenic shock, or with incomplete data may not benefit from findings applicable to this cohort.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines if geographic mismatch independently forecasts short-term major adverse cardiovascular events in patients undergoing long drug-eluting stent implantation during PCI. It builds on known risk factors for adverse outcomes after PCI and seeks to isolate the potential impact of geographic mismatch on post-procedure events. The analysis will involve patients who receive a DES of at least 38 mm and will exclude those with bare-metal stents, cardiogenic shock, in-stent restenosis, prior stents in the target segment, or limited follow-up. Data collection covers clinical, angiographic, and procedural variables to determine any independent association with short-term outcomes. The setting is Sohag University, focusing on patients treated at that institution.

Why it matters

Potential benefit: If geographic mismatch is found to predict short-term events, clinicians may improve risk stratification and post-PCI monitoring for high-risk patients.

How similar studies have gone: Evidence from previous PCI studies has identified multiple predictors of adverse events, but the specific role of geographic mismatch remains an area of investigation with mixed findings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥18 years old.
* Both sexes.
* Patients undergo percutaneous coronary intervention (PCI) with successful implantation of a drug-eluting stent (DES) measuring ≥38 mm in length.
* Successful stent deployment with discharge after PCI.

Exclusion Criteria:

* Bare-metal stent (BMS) implantation.
* Cardiogenic shock at presentation.
* In-stent restenosis lesions.
* Previous stent implantation in the target coronary segment.
* Life expectancy \<6 months due to non-cardiac causes.
* Incomplete clinical or geographic data.
* Patients lost to follow-up immediately after hospital discharge.

Where it's running

  • Sohag University
    Sohag, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.