Is geographic mismatch linked to short-term major heart problems after long drug-eluting stent placement?
Official title: Geographic Mismatch as A Predictor of Short-Term Major Adverse Cardiovascular Events Following Long Coronary Stent Implantation; A Prospective Cohort Study
Run by Sohag University · NCT07890181 · Data updated 2026-11-12
This study checks whether geographic mismatch can predict short-term major adverse cardiovascular events after a long drug-eluting stent is placed in the coronary arteries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 650 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Status | Recruiting |
| Started | September 1, 2026 |
| Main results expected | May 1, 2027 |
| Study ends | May 1, 2027 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07890181 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 and older undergoing PCI with successful DES implantation of at least 38 mm in length and discharged after the procedure.
✕Probably not a fit
Patients receiving bare-metal stents, those with cardiogenic shock, or with incomplete data may not benefit from findings applicable to this cohort.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines if geographic mismatch independently forecasts short-term major adverse cardiovascular events in patients undergoing long drug-eluting stent implantation during PCI. It builds on known risk factors for adverse outcomes after PCI and seeks to isolate the potential impact of geographic mismatch on post-procedure events. The analysis will involve patients who receive a DES of at least 38 mm and will exclude those with bare-metal stents, cardiogenic shock, in-stent restenosis, prior stents in the target segment, or limited follow-up. Data collection covers clinical, angiographic, and procedural variables to determine any independent association with short-term outcomes. The setting is Sohag University, focusing on patients treated at that institution.
Why it matters
Potential benefit: If geographic mismatch is found to predict short-term events, clinicians may improve risk stratification and post-PCI monitoring for high-risk patients.
How similar studies have gone: Evidence from previous PCI studies has identified multiple predictors of adverse events, but the specific role of geographic mismatch remains an area of investigation with mixed findings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years old. * Both sexes. * Patients undergo percutaneous coronary intervention (PCI) with successful implantation of a drug-eluting stent (DES) measuring ≥38 mm in length. * Successful stent deployment with discharge after PCI. Exclusion Criteria: * Bare-metal stent (BMS) implantation. * Cardiogenic shock at presentation. * In-stent restenosis lesions. * Previous stent implantation in the target coronary segment. * Life expectancy \<6 months due to non-cardiac causes. * Incomplete clinical or geographic data. * Patients lost to follow-up immediately after hospital discharge.
Where it's running
-
Sohag University
Sohag, Egypt Recruiting
Study contacts
- Study coordinator: Remon S Adly, MD
- Email: remonsaleh@yahoo.com
- Phone: 00201221878986
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.