Transcatheter aortic valve replacement for severe aortic valve disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on transcatheter aortic valve replacement (TAVR) as a treatment for severe aortic stenosis and aortic regurgitation. It aims to create a prospective, multicenter database to gather real-world data addressing various clinical questions related to TAVR, such as its effectiveness in younger patients, valve durability, and complications like valve leaflet thrombosis. By analyzing this data, the study seeks to enhance understanding of TAVR outcomes and inform clinical practices.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Clinical diagnosis of severe aortic stenosis or aortic regurgitation
2. Patients undergo transcatheter aortic valve replacement

Exclusion Criteria:

patients refuse the clinical follow-up

Where it's running

• Nanjing First Hospital
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Jun-Jie Zhang, MD
• Email: jameszll@163.com
• Phone: +86-25-52271350

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• KONECT RESILIA Aortic Valved Conduit real-world use in adults needing valve and ascending aorta replacement

  This study tests how the KONECT RESILIA aortic valved conduit performs in adults needing aortic valve and ascending aorta replacement.

  Recruiting at 3 sites Edwards Lifesciences · München, Bavaria and 2 other locations · NCT07619872

• Savvywire versus standard LV guidewires during transfemoral TAVI

  For people 50 and older having transfemoral TAVI, researchers will compare the Savvywire and standard LV guidewires to see if the Savvywire improves pacing and procedure-related blood flow.

  Recruiting Catharina Ziekenhuis Eindhoven · Eindhoven, North Brabant · NCT07366671

• EmStop Embolic Protection System for TAVR in Aortic Valve Stenosis

  This study tests whether the EmStop protective device can safely capture and remove debris during transcatheter aortic valve replacement in adults with severe aortic valve stenosis.

  Recruiting at 7 sites EmStop Inc · Thousand Oaks, California and 6 other locations · NCT07276711

• Tracking progression and consequences of heart valve disease

  This project will follow adults with moderate or worse valve disease to see if clinical tests and imaging can predict when their condition will get worse.

  Recruiting at 15 sites Second Affiliated Hospital, Zhejiang University, School of Medicine · Fuzhou, Fujian and 14 other locations · NCT07267117

• Real-world outcomes of the INSPIRIS RESILIA aortic valve in adults

  This registry will collect real-world data to see how the INSPIRIS RESILIA aortic valve performs in adults undergoing aortic valve replacement.

  Recruiting at 15 sites Edwards Lifesciences · Heidelberg, Baden-Wurttemberg and 14 other locations · NCT07120048

• Transcatheter JenaValve or J-Valve treatment for severe aortic regurgitation

  This project will try two transcatheter heart valves (JenaValve and J-Valve) to treat people with severe symptomatic aortic regurgitation who are high risk for open-heart surgery.

  Recruiting Prince of Wales Hospital, Shatin, Hong Kong · Hong Kong, Shatin · NCT07021612

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.