Training to improve vision in patients with Macular Degeneration
New Methods to Quantify and Train Eye Movement Strategies in Macular Degeneration
This study is testing a new training method to help people with Macular Degeneration make better use of their remaining vision and improve their daily lives.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 16 (estimated) |
| Ages | 18 Years to 89 Years |
| Sex | All |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Trial ID | NCT05456581 on ClinicalTrials.gov |
What this trial studies
This research focuses on a novel approach called 'scotoma awareness' training to assist individuals suffering from Macular Degeneration, a leading cause of central vision loss. The study aims to accelerate the development of a preferred retinal locus (PRL) by enhancing patients' awareness of their scotoma through gaze-contingent displays. By understanding individual eye movement patterns and compensatory strategies, the study seeks to create personalized rehabilitation strategies for those with severe vision impairment. The ultimate goal is to improve the quality of life for patients by maximizing their use of remaining vision.
Who should consider this trial
Good fit: Ideal candidates are individuals with severely impaired vision (20/100 or worse) due to Macular Degeneration, who have experienced this level of severity for at least two years.
Not a fit: Patients with bilateral retinal scotomas larger than 20° diameter or those unable to participate in eye tracking may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance visual function and independence for patients with Macular Degeneration.
How similar studies have performed: While this approach is innovative, previous studies have shown promise in training healthy individuals, suggesting potential for success in this population.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Severely impaired vision in both eyes (20/100 or worse) * Diagnosis of Macular Degeneration * Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (SLO, MAIA) * Medical record review indicates this disease severity level has been present for at least 2 years. Exclusion Criteria: * Inability to sit still in eye tracker for extended periods * Inability to visualize iris on video eye tracker * Bilateral retinal scotomas larger than 20° diameter
Where this trial is running
Birmingham, Alabama
- UAB — Birmingham, Alabama, United States (Recruiting)
Study contacts
- Study coordinator: Rachel Chua
- Email: r2chel@uab.edu
- Phone: 2059340497
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.