Training to help smokers manage withdrawal symptoms for quitting smoking
Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation
This study is testing a new program to help adult smokers manage feelings of anxiety and depression when they try to quit smoking, to see if it can improve their chances of success.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Trial ID | NCT03912194 on ClinicalTrials.gov |
What this trial studies
This study investigates a new intervention aimed at improving smoking cessation rates by focusing on negative affect withdrawal (NAW) regulation. It will evaluate the effectiveness of combining early withdrawal exposure with behavioral strategies to help participants manage withdrawal symptoms such as anxiety and depression. The study will involve 400 adult smokers who smoke at least 5 cigarettes per day and intend to quit, using a factorial design to assess the impact of the intervention components. The research aims to provide insights into how these strategies can enhance existing smoking cessation treatments.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who smoke at least 5 cigarettes per day and intend to quit.
Not a fit: Patients who are currently participating in another smoking cessation program or using pharmacotherapy for smoking cessation may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve smoking cessation rates and reduce the health risks associated with tobacco dependence.
How similar studies have performed: Other studies have explored similar approaches to smoking cessation, but this specific intervention focusing on NAW regulation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * at least 18 years of age * smoke at least 5 cigarettes per day * Expired breath carbon monoxide (CO) reading of at least five parts per million * report the intention to quit * reside in the Birmingham area with no plan to relocate outside of the area in the next 6 months * access to a telephone Exclusion Criteria: * inability to speak English * presence of a condition that contraindicates use of the nicotine patch * presence of conditions that might interfere with compliance with the protocol or greatly complicate treatment * any acutely life-threatening disease * concurrent participation in a formal treatment program for smoking cessation * current use of any pharmacotherapy for smoking cessation
Where this trial is running
Birmingham, Alabama
- Ryals Public Health Building — Birmingham, Alabama, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.