Clinical trial Recruiting at 1 site Interventional Ages 40 to 60

Training programs to reduce fatigue in stroke survivors

Official title: Effects Of Graded Activity Training and Task-Oriented Training on Fatigue in Post-Stroke Patients

Run by Riphah International University · NCT06846177 · Data updated 2026-11-12

This study tests if two different training programs can help stroke survivors aged 40 to 60 feel less tired and improve their energy and mobility.

Quick facts

Study typeInterventional
Ages40 Years to 60 Years
SexAll
Enrollment20 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Mansehra, KPK)
StatusRecruiting
StartedMarch 1, 2025
Main results expectedMarch 20, 2026
Study endsApril 25, 2026
Registry record updatedMarch 11, 2025
Trial IDNCT06846177 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are stroke survivors aged 40 to 60 who have experienced a stroke more than four months prior and have a fatigue score of 40 or more.

Probably not a fit

Patients with severe comorbid health conditions or those on medications that may hinder their ability to participate in physical training will likely not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial aims to evaluate the effects of Graded Activity Training and Task-Oriented Training on post-stroke fatigue in patients. The study focuses on stroke survivors aged 40 to 60 who experience significant fatigue, assessing how these training interventions can improve their energy levels and overall quality of life. By addressing the bidirectional relationship between physical deconditioning and fatigue, the trial seeks to develop a more effective intervention protocol for managing post-stroke fatigue. Additionally, it will examine the impact of these interventions on mobility and gait.

Why it matters

Potential benefit: If successful, this study could significantly enhance the quality of life for stroke survivors by reducing fatigue and improving their physical capabilities.

How similar studies have gone: While there is limited research specifically on post-stroke fatigue, similar approaches in physical rehabilitation have shown promise in improving patient outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Both male and female of age 40 to 60 years.
* Patient with both ischemic or hemorrhagic stroke.
* Patient with both right and left hemiplegia.
* Checklist Individual (CIS-F) fatigue score of 40 or more.
* Patients who had sustained a stroke more than 4 months before recruitment.
* Patients who can independently walk for 10 meters (about 33 feets)

Exclusion Criteria:

* Patients with severe comorbid health conditions (such as cardiac diseases, pulmonary diseases like COPD, Orthopedic Conditions Arthritis, joint replacements).
* Patients with uncontrolled diabetes, hypertension, Depression and Anxiety.
* Patients who are not willing to participate.
* Patient with any medications that can affect their ability to engage in physical training program like Antidepressants, Beta-Blockers, corticosteroids etc.
* Pregnant women.

Where it's running

  • Helping Hand Institute of Rehabilitation Sciences
    Mansehra, Kpk, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.