Total body irradiation for patients before stem cell transplants

Total Body Irradiation Treatments for Patients Treated at European Institute of Oncology

Observational European Institute of Oncology · NCT06335277

This study looks at how total body irradiation before stem cell transplants affects patients to see how well it works and how they tolerate it.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorEuropean Institute of Oncology Academic / other
Drugs / interventionschemotherapy
Locations1 site (Milan)
Trial IDNCT06335277 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients undergoing total body irradiation (TBI) as part of their preparation for bone marrow or peripheral stem cell transplantation. TBI is utilized to suppress the immune system and eliminate remaining cancer cells after chemotherapy. The study aims to collect and analyze data from these treatments to improve understanding of their effectiveness and tolerance. By gathering information from a diverse patient population, the research seeks to identify optimal treatment parameters and clinical situations that enhance patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are patients who are set to receive total body irradiation as part of their treatment for leukemia, lymphoma, or aplastic anemia.

Not a fit: Patients who are not undergoing total body irradiation will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment protocols for patients undergoing stem cell transplants, enhancing their chances of recovery.

How similar studies have performed: While TBI has been a standard treatment for many years, this study aims to refine its application and effectiveness, contributing to ongoing research in this area.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients undergoing total body irradiation as candidates for bone marrow or peripheral stem cell transplantation.
2. Signed informed consent

Exclusion Criteria:

* Patients who do not undergo total body irradiation

Where this trial is running

Milan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions LeukemiaLeukemia, ChronicLeukemia, AcuteLymphomaAplastic Anemia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.