Topical treatment options for acne management

Factors Affecting Medication Adherence to Topical Acne Medications: a Single-center, Prospective Study Evaluating the Adherence and Patient Satisfaction to Single and Multiple Topical Acne Medications

Early Phase 1 Interventional Wake Forest University Health Sciences · NCT05582434

This study tests different creams for acne to see if they help people stick to their treatment and improve their skin.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Enrollment72 (estimated)
Ages18 Years to 85 Years
SexAll
SponsorWake Forest University Health Sciences Academic / other
Locations1 site (Winston-Salem, North Carolina)
Trial IDNCT05582434 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of various topical treatments for acne, focusing on medication adherence among patients. It aims to address the challenges of both primary and secondary nonadherence to acne medications, which can lead to treatment failure and decreased quality of life. Participants will use different formulations of adapalene gel and combinations with clindamycin phosphate and benzoyl peroxide. The study will assess how these treatments impact adherence and overall outcomes in managing acne.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have a current diagnosis of acne and reside in the United States.

Not a fit: Patients under 18 years of age or those without a current diagnosis of acne will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve adherence to acne treatments, leading to better management of the condition and enhanced quality of life for patients.

How similar studies have performed: Other studies have shown success in improving adherence to topical treatments for chronic conditions, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Adult patients ≥18 years of age
2. Patients with a current diagnosis of acne
3. Patients who live in the US,
4. Patients have sufficient command of the English language

Exclusion Criteria:

1. Patients less than the age of 18
2. Patients without a current diagnosis of acne
3. Patients who do not live in the US
4. Patients without a sufficient command of the English language

Where this trial is running

Winston-Salem, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acne
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.