Tool for screening and diagnosing lower limb lymphedema in cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to develop a clinical screening, diagnostic, and evaluation tool specifically for patients suffering from lower limb lymphedema, particularly those with a history of skin melanoma, gynecological cancer, or urogenital cancer. The study focuses on patients who are undergoing surgical procedures that may increase their risk of developing lymphedema, such as lymph node dissection. By assessing various risk factors and clinical parameters, the study seeks to improve early detection and management of this chronic condition. The findings could lead to better patient outcomes and quality of life for cancer survivors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a diagnosis of skin melanoma (at the level of the lower limb, at least cancer stage 3), gynecological cancer, uro-genital cancer that will receive surgery (sentinel lymph node biopsy and/or (para-aortic/inguinal/pelvic) lymph node dissection)

Exclusion Criteria:

* Pregnant participants
* Presence of chronic venous insufficiency C4, C5, C6; deep venous thrombosis; post-thrombotic syndrome
* Presence of skin infections of wounds at the level of the lower limbs at the moment of inclusion

Where it's running

• University Hospitals of Leuven
  Leuven, Belgium Recruiting

Study contacts

• Principal investigator: Tessa De Vrieze, Dr. — KU Leuven
• Study coordinator: Tessa De Vrieze, Dr.
• Email: tessa.devrieze@kuleuven.be
• Phone: 003216345006

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Hydrotherapy for treating unilateral lower limb lymphedema

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  Recruiting Gaziosmanpasa Research and Education Hospital · Istanbul · NCT06839885

• Impact of Lymphoedema and Urinary Issues After Cancer Surgery

  This study looks at how common swelling in the legs and urinary problems are after cancer surgery to see if certain tests can help catch these issues early and improve life for patients.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Flanders · NCT05300308

• Extracorporeal Shock Wave Therapy to Help Lower-Limb Lymphedema (with standard CDT)

  This trial tests whether adding extracorporeal shock wave therapy to standard decongestive therapy helps people with lower-limb lymphedema.

  Recruiting Gazi University · Ankara, Yenimahalle · NCT07626645

• Using shock wave therapy to treat lower limb lymphedema

  This study is testing if adding shock wave therapy to regular treatments can help people with lower limb lymphedema feel better.

  Recruiting Parc de Salut Mar · Barcelona · NCT06454734

• Comparing lymphaticovenous anastomosis to sham surgery for cancer-related lymphedema

  This study is testing if a new surgery for cancer-related lymphedema can help people feel better compared to a fake surgery.

  Recruiting at 3 sites Maastricht University Medical Center · Nijmegen, Gelderland and 2 other locations · NCT06082349

• Evaluating new MRI techniques for lymphedema

  This study is testing new MRI techniques to better understand and track lymphedema in breast cancer patients to improve their treatment outcomes.

  Recruiting National Taiwan University Hospital · Taipei · NCT05804643

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.