Timing of manual placenta removal after delivery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Pregnant women having a term, spontaneous vaginal delivery with epidural analgesia are randomly assigned to remove the placenta manually at 15 minutes or to wait 30 minutes before manual removal. All participants receive standard third-stage-of-labor care, including oxytocin and antibiotics as needed. The main outcome is the drop in hemoglobin after delivery, with secondary outcomes like transfusion rate, satisfaction, time to first breastfeeding, hospital stay, and infection monitored. If active bleeding occurs, clinicians remove the placenta per usual care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Term spontaneous vaginal delivery.
* Singleton Pregnancy.
* Epidural Analgesia during delivery.
* Age between 18 and 45 years.

Exclusion Criteria:

* Active bleeding after delivery that warrants prompt removal of placenta regardless of time from delivery.
* Vacuum Extraction.
* Intrapartum Infection.
* Intrapartum fever above 38 degrees celsius.
* Wide 3rd and 4th degree perineal tears that mandate suturing under general anaesthesia.
* Thalassemia Carriers.

Where it's running

• Holy Family Hospital
  Nazareth, Israel Recruiting

Study contacts

• Study coordinator: Mais Abu Nofal, M.D.
• Email: maisabunofal@gmail.com
• Phone: 972522245049

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.