Time-restricted feeding for critically ill patients
The Safety and Feasibility of a 12-hour Time-Limited Enteral Feeding Protocol in Critically Ill Adults
NA · University of Kansas Medical Center · NCT06741761
This study is testing if a 12-hour feeding schedule is safe and effective for critically ill patients compared to the usual 24-hour feeding to see how it affects their health and recovery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Kansas Medical Center (other) |
| Locations | 1 site (Kansas City, Kansas) |
| Trial ID | NCT06741761 on ClinicalTrials.gov |
What this trial studies
This study assesses the feasibility and safety of a 12-hour enteral feeding protocol compared to a standard 24-hour feeding protocol in critically ill patients. The goal is to determine how these different feeding schedules impact feeding tolerance, blood sugar control, and other health factors. The trial will involve a 10-day intervention period where participants will be monitored for safety and effectiveness of the feeding protocols. Investigators aim to gather preliminary data on the effects of time-restricted feeding on glycemic control, sleep, and long-term outcomes in critical care.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are critically ill and receiving continuous enteral nutrition in an intensive care unit.
Not a fit: Patients who are on comfort measures only, have recent GI surgeries, or are expected to undergo procedures requiring removal of study devices may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve nutritional management and overall recovery for critically ill patients.
How similar studies have performed: While time-restricted feeding is a novel approach in critical care, similar studies in other populations have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (≥18 years of age) * With critical illness (hospitalized in an intensive care unit with a status of "ICU") * Who have received orders for continuous enteral nutrition Exclusion Criteria: * "Comfort Measures Only" status * Have orders to receive trickle feedings (feeding rate ≤10mL/hr) * Recent surgical procedure on the GI tract (within previous 5 days at time of recruitment) or admission for GI bleed * Receiving continuous sedation * Expected to undergo a procedure requiring removal of study devices in the three days following enrollment * History of malabsorptive bariatric surgery * Admitted for a burn injury * Known intolerance to feeding rates \>100mL/hr * Current diagnosis of pancreatitis, ileus or gastroparesis (only if using a gastrostomy tube) * Requiring intermittent or continuous renal replacement therapy * Pregnant or lactating * On an intermittent feeding schedule * Nutritional needs would require a rate higher than 120mL/hr on TRF12 protocol * Lack of clearance by primary physician
Where this trial is running
Kansas City, Kansas
- University Of Kansas Health System — Kansas City, Kansas, United States (RECRUITING)
Study contacts
- Principal investigator: Felicia Steger, PhD, MS, RD — University of Kansas Medical Center
- Study coordinator: Felicia Steger, PhD, MS, RD
- Email: fsteger@kumc.edu
- Phone: 913-945-5822
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Critical Illness, time-restricted feeding, enteral feeding, critical illness, intermittent fasting