Clinical trial Recruiting at 1 site Observational Ages 18 to 65

Tibial nerve size and clinical features in chronic plantar fasciitis

Official title: Relationship of Tibial Nerve Cross-Sectional Area in the Tarsal Tunnel to Plantar Fascia Thickness, Pressure Pain Threshold, Foot Posture, and Functional Status in Individuals With Chronic Plantar Fasciitis

Run by Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · NCT07878273 · Data updated 2026-11-12

This study tests whether the size of the tibial nerve is related to plantar fascia thickness, pain sensitivity, foot posture, and function in people with long-standing plantar fasciitis.

More Plantar Fasciitis trials

Quick facts

Study typeObservational
Ages18 Years to 65 Years
SexAll
Enrollment102 (estimated)
SponsorSultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Academic / other
Drugs / interventionsradiation
Locations1 site (Istanbul)
StatusRecruiting
StartedSeptember 7, 2026
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedOctober 16, 2026
Trial IDNCT07878273 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18-65 with chronic plantar fasciitis (heel pain for 6+ months, morning stiffness, tenderness at the medial calcaneal tubercle).

Probably not a fit

Patients without tibial nerve or plantar fascia changes related to their symptoms may not experience a direct benefit from the findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This cross-sectional observational study uses ultrasound and clinical assessments to explore associations between tibial nerve cross-sectional area at the tarsal tunnel and measures of plantar fascia thickness, pressure pain threshold, foot posture, and functional status in adults with chronic plantar fasciitis. The goal is to see if tibial nerve morphology helps explain why some patients have more pain or disability than would be expected from plantar fascia thickness alone. Findings could inform future prospective research and help identify additional targets for managing chronic plantar fasciitis. The study does not establish causation due to its observational design. Participants will undergo pressure pain threshold testing and bilateral ultrasonographic assessments of the plantar fascia and tibial nerve.

Why it matters

Potential benefit: If associations are found, results could guide more comprehensive assessments and potentially broaden targets for treatment in chronic plantar fasciitis.

How similar studies have gone: Earlier research has shown relationships between plantar fascia features and pain, but the role of tibial nerve morphology in chronic plantar fasciitis is less well established and translationally exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
1. Chronic Plantar Fasciitis Group:

   Inclusion Criteria:
   * Be between the ages of 18-65
   * Have heel pain that has been ongoing for at least 6 months, especially noticeable during the first few steps after getting up in the morning
   * Have tenderness upon palpation of the medial calcaneal tubercle
   * Have read and signed the volunteer consent form (VCF)

   Exclusion Criteria:
   * Being under 18 or over 65 years old
   * Having a history of physical therapy, injection, radiation, or surgery targeting the plantar fascia or tibial nerve within the last 6 months
   * Calcaneus fracture, tumour, or cyst related to the plantar fascia
   * Lumbosacral radiculopathy, polyneuropathy
   * Rheumatic diseases such as rheumatoid arthritis, ankylosing spondylitis, gout
   * Foot and ankle osteoarthritis
   * Presence of osteomyelitis or skin infection in the foot
   * Systemic diseases such as kidney and liver failure, diabetes, peripheral arterial vascular disease
   * Pregnancy
2. Healty-control-group

Inclusion Criteria:

* Being completely healthy
* Being between 18 - 65 years old
* Having read and signed the Volunteer Consent Form (BGOF)

Exclusion Criteria:

* Being under 18 or over 65 years old
* Having any acute or chronic disease
* Pregnancy

Where it's running

  • Sultan Abdülhamid Han Eğitim ve Araştırma Hastanesi
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.