Platelet-rich plasma treatment for patellar, Achilles, elbow (epicondylitis), and plantar heel tendinopathies.
Official title: Multicenter Real-World Evidence (RWE) Study: Evaluation of Platelet-Rich Plasma (PRP) Treatment in Tendinopathies
Run by ReSport Clinic · NCT07558564 · Data updated 2026-11-12
This multicenter observational project will try platelet-rich plasma (PRP) injections to see if they reduce pain and improve function in adults with chronic patellar, Achilles, lateral elbow (epicondylitis), or plantar heel (fasciitis) tendinopathies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | ReSport Clinic Academic / other |
| Locations | 5 sites (A Coruña and 4 other locations) |
| Status | Recruiting |
| Started | April 2026 |
| Main results expected | March 2028 |
| Study ends | March 2028 |
| Registry record updated | April 30, 2026 |
| Trial ID | NCT07558564 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age >18) with a clinical or ultrasound diagnosis of chronic patellar, Achilles, lateral epicondylitis, or plantar fasciitis who can give informed consent and complete 12 months of follow-up and have a platelet count ≥100 × 10⁹/L.
✕Probably not a fit
Patients with recent tendon surgery, corticosteroid injection within the last month, systemic inflammatory disease, coagulopathy or anticoagulant therapy, low platelet counts, or who are pregnant or breastfeeding are excluded and unlikely to receive benefit under this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, multicenter, real-world evidence cohort collecting data on PRP treatment for four common tendinopathies. Participating centers will record clinical variables, treatment protocols, and outcomes over 12 months while characterizing PRP preparations using hematology analyzers and the BioSmartData® platform. The design is observational, so treatments follow routine clinical practice rather than a randomized protocol. Adults with chronic (>6 weeks) tendon symptoms who can consent and complete follow-up are eligible, while recent surgery, recent corticosteroid injection, systemic inflammatory disease, coagulopathy/anticoagulant use, low platelet counts, pregnancy, or breastfeeding are exclusions.
Why it matters
Potential benefit: If successful, PRP could offer a minimally invasive option that reduces pain and improves function for people with chronic tendinopathies.
How similar studies have gone: Previous randomized trials and meta-analyses report mixed results for PRP in tendinopathies, with some positive findings for lateral epicondylitis and plantar fasciitis but inconsistent outcomes for Achilles and patellar tendons.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical and/or ultrasound diagnosis of chronic tendinopathy (duration \>6 weeks) * Age \>18 years * Provision of written informed consent * Willingness and ability to complete follow-up assessments for 12 months Exclusion Criteria: * Surgical treatment of the affected tendon within the previous 6 months * Corticosteroid injection within the last month * Systemic inflammatory disease (e.g., rheumatoid arthritis) * Coagulopathies or ongoing anticoagulant therapy * Complete blood count showing a platelet concentration \<100 × 10⁹/L (to exclude patients with potential thrombocytopenia) * Pregnancy or breastfeeding
Where it's running
-
Instituto Médico Arriaza
A Coruña, Spain Recruiting -
Instituto Cugat
Barcelona, Spain Recruiting -
ReSport Clinic
Barcelona, Spain Recruiting -
Ripoll y dePrado Medical Group
Madrid, Spain Recruiting -
Hospital MIKS
Vitoria-Gasteiz, Spain Recruiting
Study contacts
- Principal investigator: Ferran Abat Gonzalez, MD PhD — ReSport Clinic
- Study coordinator: Resport Clinic, MD PhD
- Email: abat@resportclinic.com
- Phone: +34 93 2778709
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.