Three-Needle Dazhui with Electroacupuncture for cervical spondylosis with wind-cold
Official title: Three-Needle Dazhui Combined With Electroacupuncture for Cervical Spondylotic Radiculopathy and Wind-Cold Syndrome: A Randomized, Single-Blind, Controlled Trial Evaluating Pain and Neck Disability
Run by University of Medicine and Pharmacy at Ho Chi Minh City · NCT07640126 · Data updated 2026-11-12
This trial tests whether adding the Three-Needle Dazhui acupuncture technique to standard electroacupuncture helps reduce neck pain and improve neck function in adults with cervical spondylosis and wind-cold syndrome.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Days and up |
| Sex | All |
| Enrollment | 74 (estimated) |
| Sponsor | University of Medicine and Pharmacy at Ho Chi Minh City Academic / other |
| Locations | 1 site (Ho Chi Minh City) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | June 2028 |
| Study ends | June 2028 |
| Registry record updated | July 20, 2026 |
| Trial ID | NCT07640126 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years and older with CSR due to cervical spondylosis and wind-cold syndrome, experiencing moderate to severe neck pain (VAS ≥ 50 mm).
✕Probably not a fit
Patients with low baseline pain, non-spondylotic neck conditions, or intolerance to acupuncture may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, single-blind study compares two acupuncture approaches in adults with cervical spondylotic radiculopathy and wind-cold syndrome. The experimental group receives the Three-Needle Dazhui technique plus electroacupuncture, while the control group receives electroacupuncture alone, alongside basic traditional therapies. Treatment is given daily for 14 days, with outcomes measured at baseline, after 1 week, and at 2 weeks, focusing on pain (VAS) and neck function (NDI). Safety is monitored for adverse events related to needling. The study aims to determine if the Three-Needle Dazhui method provides additional pain relief and functional improvement over standard electroacupuncture.
Why it matters
Potential benefit: If successful, patients may experience greater pain relief and improved neck function with a non-pharmacologic therapy approach.
How similar studies have gone: Previous acupuncture-focused studies support safety and potential benefit of electroacupuncture for neck pain; this study adds a combined Three-Needle Dazhui approach to see if it improves outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consent: Participants must voluntarily agree to participate and sign a written informed consent form. * Age: Individuals aged 18 years or older. * Pain Intensity: Patients with a baseline pain score of VAS ≥ 50 mm on the Visual Analog Scale. * Modern Medicine Diagnosis (Cervical Spondylotic Radiculopathy - CSR) Patients must meet the diagnostic criteria for CSR due to cervical spondylosis according to Decision 361/QD-BYT, including: * Cervical Spine Syndrome: Localized neck pain, restricted range of motion, and tenderness upon palpation of the spinous processes or paravertebral areas. Radicular Syndrome: Neck pain radiating to the occipital region, shoulder, arm, or hand. * Physical Examination: At least one positive result from the following tests: Bell-ringer sign, Spurling's test, Shoulder abduction test, or Cervical distraction test. * Imaging Criteria: X-ray findings (straight, lateral, or 3/4 oblique views) showing at least one of the following: 1. Osteophytes (bone spurs) on the vertebral body. 2. Intervertebral disc space narrowing ≥ 25%. 3. Subchondral bone sclerosis. 4. Spondylolisthesis. - Traditional Chinese Medicine (TCM) Diagnosis (Wind-Cold Syndrome) Patients must satisfy at least one primary symptom and reach a total symptom score of ≥ 50% based on the following criteria: * Primary Symptoms: Pain in the neck and shoulder radiating to the arm accompanied by numbness; pain is the dominant feature; pain increases with cold and decreases with warmth. * Secondary Symptoms: Aversion to cold, aversion to wind, cold extremities, and presence or absence of sweating. * Tongue and Pulse: Pale tongue with a thin white coating; floating-tight or slow pulse. Exclusion Criteria: * History of neck trauma. * Diagnosed with specific bone or joint diseases: Rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Down syndrome, cervical spina bifida, or Scheuermann's disease. * Severe neurological deficits: Progressive muscle weakness (motor loss) or acute, severe sensory loss indicating advanced nerve compression. * Vertebral-basilar artery syndrome: Headache, dizziness, tinnitus, loss of balance, or fatigue. * Autonomic nervous system disorders: Pain accompanied by tinnitus, visual disturbances, or vasomotor disorders in the occipital-shoulder region or arms. * Central motor neuron lesions: Presence of Hoffmann's sign, Babinski's sign, hyperreflexia, spasticity, urinary/fecal incontinence, or sexual dysfunction. * Symptoms suggesting systemic or malignant disease: Unexplained weight loss, fever, loss of appetite, personal or family history of malignant tumors, or diffuse pain and stiffness. * Symptoms suggesting infection: Fever, meningeal signs, or photophobia. * Symptoms suggesting serious acute medical conditions: Myocardial infarction (chest pain + sweating + shortness of breath) or arterial dissection (tearing pain sensation + headache + blurred vision). * Local or systemic contraindications: Infection or ulceration at the acupuncture site; patients who are exhausted, emaciated, or suffering from severe accompanying internal medical diseases. * Substance abuse: Alcohol or drug addiction. * Recent medication use (within the past month): Currently using analgesics or anti-inflammatory drugs that may affect results, such as Opioids, NSAIDs, Corticosteroids, Gabapentin, Pregabalin, or tricyclic antidepressants. * Other ongoing treatments: Currently undergoing other therapies such as acupressure, massage, or physical therapy for the neck area.
Where it's running
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University of Medicine and Pharmacy at Ho Chi Minh City
Ho Chi Minh City, Vietnam Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.