Clinical trial Recruiting at 1 site Interventional Ages 18 Days and up

Three-Needle Dazhui with Electroacupuncture for cervical spondylosis with wind-cold

Official title: Three-Needle Dazhui Combined With Electroacupuncture for Cervical Spondylotic Radiculopathy and Wind-Cold Syndrome: A Randomized, Single-Blind, Controlled Trial Evaluating Pain and Neck Disability

Run by University of Medicine and Pharmacy at Ho Chi Minh City · NCT07640126 · Data updated 2026-11-12

This trial tests whether adding the Three-Needle Dazhui acupuncture technique to standard electroacupuncture helps reduce neck pain and improve neck function in adults with cervical spondylosis and wind-cold syndrome.

Quick facts

Study typeInterventional
Ages18 Days and up
SexAll
Enrollment74 (estimated)
SponsorUniversity of Medicine and Pharmacy at Ho Chi Minh City
Academic / other
Locations1 site (Ho Chi Minh City)
StatusRecruiting
StartedJune 1, 2026
Main results expectedJune 2028
Study endsJune 2028
Registry record updatedJuly 20, 2026
Trial IDNCT07640126 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years and older with CSR due to cervical spondylosis and wind-cold syndrome, experiencing moderate to severe neck pain (VAS ≥ 50 mm).

Probably not a fit

Patients with low baseline pain, non-spondylotic neck conditions, or intolerance to acupuncture may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, single-blind study compares two acupuncture approaches in adults with cervical spondylotic radiculopathy and wind-cold syndrome. The experimental group receives the Three-Needle Dazhui technique plus electroacupuncture, while the control group receives electroacupuncture alone, alongside basic traditional therapies. Treatment is given daily for 14 days, with outcomes measured at baseline, after 1 week, and at 2 weeks, focusing on pain (VAS) and neck function (NDI). Safety is monitored for adverse events related to needling. The study aims to determine if the Three-Needle Dazhui method provides additional pain relief and functional improvement over standard electroacupuncture.

Why it matters

Potential benefit: If successful, patients may experience greater pain relief and improved neck function with a non-pharmacologic therapy approach.

How similar studies have gone: Previous acupuncture-focused studies support safety and potential benefit of electroacupuncture for neck pain; this study adds a combined Three-Needle Dazhui approach to see if it improves outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Consent: Participants must voluntarily agree to participate and sign a written informed consent form.
* Age: Individuals aged 18 years or older.
* Pain Intensity: Patients with a baseline pain score of VAS ≥ 50 mm on the Visual Analog Scale.
* Modern Medicine Diagnosis (Cervical Spondylotic Radiculopathy - CSR) Patients must meet the diagnostic criteria for CSR due to cervical spondylosis according to Decision 361/QD-BYT, including:

  * Cervical Spine Syndrome: Localized neck pain, restricted range of motion, and tenderness upon palpation of the spinous processes or paravertebral areas.

Radicular Syndrome: Neck pain radiating to the occipital region, shoulder, arm, or hand.

* Physical Examination: At least one positive result from the following tests: Bell-ringer sign, Spurling's test, Shoulder abduction test, or Cervical distraction test.
* Imaging Criteria: X-ray findings (straight, lateral, or 3/4 oblique views) showing at least one of the following:

  1. Osteophytes (bone spurs) on the vertebral body.
  2. Intervertebral disc space narrowing ≥ 25%.
  3. Subchondral bone sclerosis.
  4. Spondylolisthesis. - Traditional Chinese Medicine (TCM) Diagnosis (Wind-Cold Syndrome) Patients must satisfy at least one primary symptom and reach a total symptom score of ≥ 50% based on the following criteria:
* Primary Symptoms: Pain in the neck and shoulder radiating to the arm accompanied by numbness; pain is the dominant feature; pain increases with cold and decreases with warmth.
* Secondary Symptoms: Aversion to cold, aversion to wind, cold extremities, and presence or absence of sweating.
* Tongue and Pulse: Pale tongue with a thin white coating; floating-tight or slow pulse.

Exclusion Criteria:

* History of neck trauma.
* Diagnosed with specific bone or joint diseases: Rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Down syndrome, cervical spina bifida, or Scheuermann's disease.
* Severe neurological deficits: Progressive muscle weakness (motor loss) or acute, severe sensory loss indicating advanced nerve compression.
* Vertebral-basilar artery syndrome: Headache, dizziness, tinnitus, loss of balance, or fatigue.
* Autonomic nervous system disorders: Pain accompanied by tinnitus, visual disturbances, or vasomotor disorders in the occipital-shoulder region or arms.
* Central motor neuron lesions: Presence of Hoffmann's sign, Babinski's sign, hyperreflexia, spasticity, urinary/fecal incontinence, or sexual dysfunction.
* Symptoms suggesting systemic or malignant disease: Unexplained weight loss, fever, loss of appetite, personal or family history of malignant tumors, or diffuse pain and stiffness.
* Symptoms suggesting infection: Fever, meningeal signs, or photophobia.
* Symptoms suggesting serious acute medical conditions: Myocardial infarction (chest pain + sweating + shortness of breath) or arterial dissection (tearing pain sensation + headache + blurred vision).
* Local or systemic contraindications: Infection or ulceration at the acupuncture site; patients who are exhausted, emaciated, or suffering from severe accompanying internal medical diseases.
* Substance abuse: Alcohol or drug addiction.
* Recent medication use (within the past month): Currently using analgesics or anti-inflammatory drugs that may affect results, such as Opioids, NSAIDs, Corticosteroids, Gabapentin, Pregabalin, or tricyclic antidepressants.
* Other ongoing treatments: Currently undergoing other therapies such as acupressure, massage, or physical therapy for the neck area.

Where it's running

  • University of Medicine and Pharmacy at Ho Chi Minh City
    Ho Chi Minh City, Vietnam
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.