Identifying factors that improve neck pain after cervical spine surgery

Predictors of Axial Pain Improvement After Anterior Cervical Discectomy and Fusion - Prospective, Observational Study

Observational Medical University of Warsaw · NCT06601634

This study looks at what factors can help people with neck pain feel better after having surgery to fix their cervical spine.

Quick facts

Study typeObservational
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorMedical University of Warsaw Academic / other
Locations2 sites (Krakow, Lesser Poland Voivodeship and 1 other locations)
Trial IDNCT06601634 on ClinicalTrials.gov

What this trial studies

This observational study aims to analyze the outcomes of anterior cervical discectomy and fusion (ACDF) in patients suffering from neck pain due to degenerative cervical conditions. It seeks to identify predictors that may indicate which patients are likely to experience significant improvement in their axial neck pain following the procedure. By focusing on a specific patient population eligible for ACDF, the study will gather data on pain reduction and other relevant outcomes. The findings could enhance understanding of patient selection for ACDF in the context of neck pain management.

Who should consider this trial

Good fit: Ideal candidates for this study are patients eligible for one- or two-level ACDF due to degenerative cervical pathology.

Not a fit: Patients with previous cervical spine surgery, trauma, or other specific diseases causing neck pain may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify which patients are most likely to benefit from ACDF, leading to improved treatment strategies for neck pain.

How similar studies have performed: While there is existing literature on ACDF's effectiveness for neck pain, this study's focus on identifying specific predictors of improvement is a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ability to provide informed consent
* Patients who are qualified for one- or two-level ACDF for the treatment of degenerative cervical pathology

Exclusion Criteria:

* Previous cervical spine surgery
* Previous cervical spine trauma
* Other diseases causing neck pain include rheumatoid arthritis, lupus, polymyalgia rheumatica, myositis, seronegative inflammatory diseases, and fibromyalgia
* Drug abuse
* Myelopathy
* Spinal infection
* VAS neck pain score less than 3 (Inability to achieve an MCID which is calculated as 2.5 for the VAS scale)

Where this trial is running

Krakow, Lesser Poland Voivodeship and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Neck PainCervical SpondylosisCervical Disc Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.