Three-minute eyelid closure to improve corneal curvature readings
Official title: The Effect of Eyelid Closure on the Quality Index of Keratometric Measurements: a Non-controlled Interventional Study
Run by Vienna Institute for Research in Ocular Surgery · NCT07297849 · Data updated 2026-11-12
This tests whether gently closing the eyelid for three minutes before corneal measurements helps improve keratometry accuracy for adults with a 'warning' keratometry quality index who are planning cataract surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 29 (estimated) |
| Sponsor | Vienna Institute for Research in Ocular Surgery Academic / other |
| Locations | 1 site (Vienna, State of Vienna) |
| Status | Recruiting |
| Started | November 7, 2024 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | December 22, 2025 |
| Trial ID | NCT07297849 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age 18+) preparing for cataract surgery who have a keratometry quality index of "warning" and can voluntarily and fully close their eyelids are ideal candidates.
✕Probably not a fit
Patients with severe corneal scarring or other conditions that compromise corneal integrity, recent ocular surgery, inability to close the eyelid, or unstable ocular surface disease are unlikely to benefit from this eyelid-closure intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-site interventional protocol enrolls adults with a keratometry quality index flagged as "warning" and compares keratometry measurements before and after a three-minute period of eyelid closure. The procedure is noninvasive: standard preoperative corneal curvature (keratometry) is recorded, the participant closes the eyelid for three minutes, and keratometry is repeated to detect changes in measurement quality. Patients with severe corneal disease, recent ocular surgery, pregnancy or inability to close the eyelid are excluded. The trial is conducted at the Vienna Institute for Research in Ocular Surgery and focuses on a simple, low-risk maneuver to stabilize the tear film and reduce measurement error.
Why it matters
Potential benefit: If successful, this simple maneuver could reduce preoperative keratometry error and help achieve more accurate refractive outcomes after cataract surgery.
How similar studies have gone: Prior research shows tear film stability and osmolarity affect keratometry precision and that treating dry eye can improve measurements, but brief eyelid closure as a corrective maneuver has been relatively little studied and is a novel, low-tech approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 or older * Written informed consent * Keratometry quality index "warning" Exclusion Criteria: * Severe corneal conditions that may compromise corneal integrity (such as corneal scarring, etc.) * Pregnancy (pregnancy test will be taken in women of reproductive age), nursing women * Ocular surgery in the study eye in the three months preceding the study * Inability of visual fixation (e.g. in patients with nystagmus) * Inability of eyelid closure (e.g. in patients with facial nerve paralysis)
Where it's running
-
Vienna Institute for Research in Ocular Surgery (VIROS), Department of Ophthalmology
Vienna, State of Vienna, Austria Recruiting
Study contacts
- Study coordinator: Andreas Schlatter, MD
- Email: office@viros.at
- Phone: +43 1 91021 57564
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.