Thoracolumbar fascia mobilization versus ultrasound-guided 5% dextrose injection for chronic low back pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized interventional trial compares hands-on thoracolumbar fascia mobilization with ultrasound-guided interfascial injections of 5% dextrose in adults who have nonspecific chronic low back pain. Participants are assigned to one of three groups, with the mobilization group receiving standardized myofascial release twice weekly for three weeks and the injection group treated under ultrasound guidance to the thoracolumbar interfascial space. Primary outcomes include pain intensity, lumbar range of motion, and functional disability, while secondary outcomes include quality of life, proprioception, and thoracolumbar fascia thickness and echogenicity. Eligible participants are adults aged 18–65 without prior spinal surgery, radiculopathy, major inflammatory or malignant disease, recent manual therapy or injections, or other exclusionary conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male or female patients aged 18 to 65 years
2. Presence of low back pain lasting longer than 3 months
3. No adequate response to medical treatment
4. Voluntary participation in the study

Exclusion Criteria:

1. Age below 18 or above 65 years
2. Body mass index (BMI) greater than 30 kg/m²
3. Pregnancy or breastfeeding
4. Presence of coagulation disorders
5. History of spinal surgery
6. Presence of inflammatory or malignant diseases
7. Local infection at the spine or injection site
8. Presence of lumbar disc pathology causing radiculopathy
9. Presence of spinal stenosis, spondylolysis, or spondylolisthesis
10. Participation in physical therapy or any manual therapy within the past 6 months
11. Receiving lumbar injections within the past 6 months
12. History of allergy to injection materials
13. Refusal to participate in the study

Where it's running

• Ankara Training and Research Hospital
  Ankara, Altındağ, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Büşra ALÇIN, Medical Doctor — Ankara Training and Research Hospital
• Study coordinator: Barış NACIR, Professor Doctor
• Email: drbarisnacir@gmail.com
• Phone: +905327278724

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.