Text messaging to improve HIV testing in LGBTQ+ teens

Effectiveness and Implementation of Text Messaging to Improve Human Immunodeficiency Virus (HIV) Testing in Adolescents

Not applicable Interventional Northwestern University · NCT06096519

This study is testing if sending motivational text messages can encourage LGBTQ+ teens to get tested for HIV more often.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment360 (estimated)
Ages13 Years to 19 Years
SexAll
SponsorNorthwestern University Academic / other
Locations1 site (Chicago, Illinois)
Trial IDNCT06096519 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a text message-based intervention aimed at increasing HIV testing behaviors among adolescent sexual minority males and transgender and gender diverse teens aged 13-18. Participants will be randomized into either a treatment group receiving motivational and behavioral skills training or a control group receiving only informational content. The study builds on a previous successful intervention, G2G, and aims to modernize and tailor the content to be inclusive of transgender and gender diverse teens. The primary outcome will be measured through self-reported HIV testing and objective evidence such as photos of test results.

Who should consider this trial

Good fit: Ideal candidates are male-identified or male sex at birth adolescents aged 13-18 who have had penetrative sex with male partners and identify as sexual and gender minorities.

Not a fit: Patients who are HIV positive, currently on PrEP, or cisgender females will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly increase HIV testing rates among at-risk adolescents, leading to earlier diagnosis and treatment.

How similar studies have performed: Previous studies, such as the G2G pilot trial, have shown success in increasing HIV testing rates through similar text-based interventions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have penetrative or oral sex in their lifetime
* 13-19 years old
* reads in English at a 8th grade level
* HIV negative or unknown status
* own a cell phone with an unlimited MMS plan and plan to have the same number during the study
* can provide informed assent, as shown on a capacity to consent assessment
* live in the U.S. or territories.

Exclusion Criteria:

* Previous lifetime testing for HIV or an STI OR no testing since last sexual experience
* HIV positive
* Currently on PrEP

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIVHuman immunodeficiency virusAdolescentsSexually transmitted infectionsSexual health
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.