Text message reminders for HPV vaccination

SEARCH II: Short Message Service (SMS) Electronic Adolescent Reminders for Completion of HPV Vaccination - Uganda: Randomized Controlled Trial

Not applicable Interventional Columbia University · NCT06161831

This study tests if sending text message and phone reminders can help preteen and teenage girls in Kampala, Uganda, get their HPV vaccinations on time.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment396 (estimated)
Ages10 Years to 14 Years
SexFemale
SponsorColumbia University Academic / other
Locations2 sites (New York, New York and 1 other locations)
Trial IDNCT06161831 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of text message and automated phone reminders to improve the initiation and completion rates of HPV vaccinations among preteen and adolescent girls in Kampala, Uganda. Conducted in collaboration with local health centers and schools, caregivers of eligible girls will be randomized to receive reminders based on their preferences. The study aims to address the low vaccination rates in the region, particularly focusing on the completion of the vaccination series. This is the first full randomized controlled trial of its kind in Sub-Saharan Africa.

Who should consider this trial

Good fit: Ideal candidates for this study are parenting adults of adolescent girls aged 10-14 years residing in Kampala who can communicate in English or Luganda.

Not a fit: Patients who do not have access to a cell phone with text messaging capability or who speak a language other than English or Luganda may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly increase HPV vaccination rates and reduce the incidence of cervical cancer in Uganda.

How similar studies have performed: Previous studies in the U.S. have shown success with text message reminders for vaccinations, but this approach has not been fully tested in a preteen/adolescent population in low and middle-income countries.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be a parenting adult of an adolescent girl aged 10-14 years
* Reside in Kampala and/or the surrounding districts
* Speak English or Luganda
* Have a cell phone with text messaging capability
* Must have ability to consent

Exclusion Criteria:

* Parenting adult speaks other language than English or Luganda only
* Parenting adult already enrolled in the study for another child
* Participation in previous HPV vaccine reminder study

Where this trial is running

New York, New York and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Human Papillomavirus VaccinationHuman papillomavirusVaccinationText messageSMSmHealthUganda
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.