Testing cognitive decline in people at risk for Alzheimer's disease
Official title: Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
Run by Neurobehavioral Systems, Inc. · NCT04800588 · Data updated 2026-11-12
This study is testing how well healthy people of different ages and backgrounds perform on brain tasks to help spot early signs of cognitive decline related to aging.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 89 Years |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Neurobehavioral Systems, Inc. Industry-sponsored |
| Locations | 1 site (Berkeley, California) |
| Status | Recruiting |
| Started | May 5, 2021 |
| Main results expected | March 31, 2027 |
| Study ends | March 31, 2027 |
| Registry record updated | May 22, 2025 |
| Trial ID | NCT04800588 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include healthy adults aged 60 to 89, as well as younger participants aged 18 to 89 who can use a computer mouse and touch screen.
✕Probably not a fit
Patients with a history of psychiatric disorders, strokes, substance abuse, or other medical conditions that affect cognitive testing may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the performance of healthy participants on computerized cognitive tasks to gather normative data for early detection of cognitive decline associated with aging. Participants are divided into groups based on age and ethnicity, with assessments conducted over three years to track changes in cognitive performance. The study aims to understand health disparities in cognitive testing and improve the reliability of cognitive assessments across diverse populations.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection of cognitive decline, allowing for timely interventions in at-risk individuals.
How similar studies have gone: Other studies have shown promise in using computerized cognitive assessments for early detection of cognitive decline, making this approach both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Must be able to use computer mouse and touch screen * Must speak English as a primary language * Must speak Spanish as a primary language (for Latino participants completing our Spanish translation) Exclusion Criteria: * History of psychiatric disorder * History of stroke or transient ischemic attack * History of substance abuse * History of medical or sensory disorders that are incompatible with effective testing * History of traumatic brain injury with hospitalization and extended loss of consciousness * History of epilepsy * History of depression or anxiety
Where it's running
-
Neurobehavioral Systems, Inc.
Berkeley, California, United States Recruiting
Study contacts
- Study coordinator: Kathleen Hall, PhD
- Email: clinical_trial_coordinator@neurobs.com
- Phone: 510-214-3176
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.