Testing cognitive decline in people at risk for Alzheimer's disease
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
This study is testing how well healthy people of different ages and backgrounds perform on brain tasks to help spot early signs of cognitive decline related to aging.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 2000 (estimated) |
| Ages | 18 Years to 89 Years |
| Sex | All |
| Sponsor | Neurobehavioral Systems, Inc. Industry-sponsored |
| Locations | 1 site (Berkeley, California) |
| Trial ID | NCT04800588 on ClinicalTrials.gov |
What this trial studies
This study evaluates the performance of healthy participants on computerized cognitive tasks to gather normative data for early detection of cognitive decline associated with aging. Participants are divided into groups based on age and ethnicity, with assessments conducted over three years to track changes in cognitive performance. The study aims to understand health disparities in cognitive testing and improve the reliability of cognitive assessments across diverse populations.
Who should consider this trial
Good fit: Ideal candidates include healthy adults aged 60 to 89, as well as younger participants aged 18 to 89 who can use a computer mouse and touch screen.
Not a fit: Patients with a history of psychiatric disorders, strokes, substance abuse, or other medical conditions that affect cognitive testing may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection of cognitive decline, allowing for timely interventions in at-risk individuals.
How similar studies have performed: Other studies have shown promise in using computerized cognitive assessments for early detection of cognitive decline, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Must be able to use computer mouse and touch screen * Must speak English as a primary language * Must speak Spanish as a primary language (for Latino participants completing our Spanish translation) Exclusion Criteria: * History of psychiatric disorder * History of stroke or transient ischemic attack * History of substance abuse * History of medical or sensory disorders that are incompatible with effective testing * History of traumatic brain injury with hospitalization and extended loss of consciousness * History of epilepsy * History of depression or anxiety
Where this trial is running
Berkeley, California
- Neurobehavioral Systems, Inc. — Berkeley, California, United States (Recruiting)
Study contacts
- Study coordinator: Kathleen Hall, PhD
- Email: clinical_trial_coordinator@neurobs.com
- Phone: 510-214-3176
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.