Testing a wearable device to measure alcohol levels in real-world settings

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

Observational University of Illinois at Urbana-Champaign · NCT05692830

This study is testing a new wearable device that measures alcohol levels in your body to see how accurately it works in everyday situations.

Quick facts

Study typeObservational
Enrollment240 (estimated)
Ages21 Years and up
SexAll
SponsorUniversity of Illinois at Urbana-Champaign Academic / other
Locations1 site (Champaign, Illinois)
Trial IDNCT05692830 on ClinicalTrials.gov

What this trial studies

This study examines the accuracy of a new wearable biosensor that measures transdermal alcohol concentration (TAC) by conducting a combined laboratory and ambulatory assessment over 14 days. Participants will wear the biosensor while also attending three laboratory sessions where they will consume controlled doses of alcohol at varying rates. The goal is to understand the relationship between TAC and breath alcohol concentration (BAC) in diverse real-world contexts. The study utilizes machine learning algorithms to analyze the data collected from participants to improve the accuracy of alcohol level estimations.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 21 and older who consume alcohol at least twice a week.

Not a fit: Patients with psychological or medical conditions contraindicating alcohol consumption or those currently seeking treatment for alcohol use disorder may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more accurate and convenient methods for monitoring alcohol consumption, potentially aiding in reducing alcohol-related harm.

How similar studies have performed: While wearable alcohol biosensors are a developing field, this specific approach combining laboratory and real-world assessments is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 21 years or older
* drink alcohol at least 2x weekly

Exclusion Criteria:

* psychological or medical conditions that might contraindicate alcohol-administration
* history of adverse reaction to type and amount of beverage used in the study
* currently seeking treatment for alcohol use disorder
* does not drink alcohol regularly
* taking drugs or medications for which alcohol consumption would be contraindicated
* women who are pregnant or are attempting to become pregnant

Where this trial is running

Champaign, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Alcohol DrinkingAlcohol Intoxicationtransdermal alcohol contentambulatorytransdermal biosensormachine learning algorithmsbreath alcohol content
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.