Testing a supplement for improving blood sugar levels in adults with prediabetes

Effect of Science Research Wellness Ndo1 on Glycaemia in Adults With Pre-diabetes

This study is testing a new supplement to see if it can help adults with prediabetes improve their blood sugar levels over 12 weeks.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 14 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Wellizen Australia (Industry-sponsored)
• Locations: 1 site (Guangzhou, Guandong)
• Trial ID: NCT06897462 on ClinicalTrials.gov

What this trial studies

This study evaluates the effects of a 12-week supplementation of SRW Ndo1 on metabolic and general health in adults diagnosed with prediabetes. Participants will take two capsules daily and will be monitored for changes in their HbA1C levels, body measurements, and blood pressure. The study includes a comparison between the supplement and a placebo to determine its effectiveness in supporting normal blood sugar metabolism. Participants are required to maintain their usual diet and lifestyle throughout the study period.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and over who have been diagnosed with prediabetes.

Not a fit: Patients with medical conditions affecting glycaemia or those currently taking other supplements that influence blood sugar may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new supplement option for managing blood sugar levels in individuals with prediabetes.

How similar studies have performed: While there have been studies on dietary supplements for glycaemic control, the specific approach of SRW Ndo1 is novel and has not been extensively tested.

Eligibility criteria

Inclusion Criteria:

1. Age 18 years and over.
2. Prediabetes, defined as fasting plasma glucose of 6.1-6.9 mmol/L and/or HbA1c of 5.7-6.4% and/or 2 h plasma glucose of 7.8-11.0 mmol/L after ingestion of 75 g of oral glucose load. Blood tests conducted within 3 months before randomisation will be accepted.
3. Able to read and write English.
4. Has access to internet.
5. Provided informed consent to participate in the study.

Exclusion Criteria:

1. Has a medical condition known to affect the glycaemia.
2. Regular intake of a health supplement with effects on glycaemia.
3. Currently participating in another trial/study of a supplement or drug.
4. Has any known food or allergy or intolerances to the ingredients of the intervention.
5. Pregnant, trying to conceive or breastfeeding.
6. Has any current substance abuse (including tobacco, alcohol and recreational drugs) or currently in substance withdrawal.
7. Moderate to severe medical conditions (defined as a significant impact on social areas of functioning).
8. Any medical conditions that was not stable over the last 3 months.
9. Taking any prescription medication known to affect glycaemia or had a change in their medication within the last 3 months.
10. Currently taking celiprolol, metformin, or any angiotensin-converting enzyme inhibitor medications.
11. Major medical or surgical event requiring hospitalization within the last 3 months.
12. Any other medical reason that may make participation in this study pose a risk to the participant, including potential herb-drug interactions, at the discretion of the study medical supervisor.

Where this trial is running

Guangzhou, Guandong

• Baohua — Guangzhou, Guandong, China (Recruiting)

Study contacts

• Study coordinator: Yoann Birling

Conditions Prediabetes; Diabetes; prediabetes