TENS at two acupuncture points and its immediate effects on pain-related brain signals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy adults participate in two randomized within-subject sessions where baseline pain-related evoked potentials (PREPs) are recorded, followed by a 20-minute low-frequency TENS application to one acupoint and a post-intervention PREP recording. The study compares PREP waveform features (N2 and P2 amplitudes and latencies) before and after TENS at Zhongzhu (SJ3) and Hegu (LI4) to detect changes in cortical nociceptive processing. Subjective pain ratings and any adverse responses are collected to evaluate tolerability alongside neurophysiological measures. Results aim to clarify whether acupoint TENS produces measurable modulation of nociceptive pathways in healthy volunteers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy Adult
* 20 years or older
* The absence of chronic medical conditions
* No history of drug allergies
* No skin disorders
* No current use of medications that could affect study outcomes
* Participants maintain a regular daily routine
* No history of substance or medication abuse

Exclusion Criteria:

* History of malignant tumors
* History of hand disorders
* Has implanted cardiac pacemakers
* Pregnancy
* Epilepsy
* Any other condition that may interfere with the study procedures

Where it's running

• Department of Physical Therapy of China Medical University
  Taichung, Beitun, Taiwan, Taiwan Recruiting

Study contacts

• Study coordinator: Yueh-Ling Hsieh
• Email: sherrie@mail.cmu.edu.tw
• Phone: 04-22053366 Ext. #7312

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.