Temporary ovarian suspension during laparoscopy to reduce postoperative adhesions
The Effect of Temporary Ovarian Suspension to the Anterior Abdominal Wall During Laparoscopic Endometriosis Surgery for Adhesion Prevention -A Comparative and Prospective Study
This study will test whether temporarily lifting and attaching the ovaries to the abdominal wall during laparoscopic surgery reduces ovarian and pelvic adhesions in people having surgery for moderate-to-severe endometriosis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 76 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Carmel Medical Center Academic / other |
| Locations | 1 site (Haifa) |
| Trial ID | NCT07087756 on ClinicalTrials.gov |
What this trial studies
This prospective, single-blinded randomized controlled trial enrolls patients with moderate-to-severe endometriosis who are at risk for ovarian adhesions and randomizes them to laparoscopic surgery with temporary ovarian suspension or to standard care without suspension. Participants complete daily questionnaires about pain and suture removal eagerness after surgery. Blinded ultrasound experts evaluate adhesion formation at about 6 and 13 weeks postoperatively, and no anti-adhesive barriers are used to reduce confounding. The trial compares adhesion rates and early postoperative symptoms between the two groups.
Who should consider this trial
Good fit: Ideal candidates are people with moderate-to-severe endometriosis and suspected ovarian or posterior pelvic adhesions (ovary, ovarian fossa, uterosacral ligaments, or pouch of Douglas) who are scheduled for laparoscopic excision and can attend follow-up visits.
Not a fit: Patients with minimal or mild endometriosis without suspected adhesions or those not undergoing endometriosis surgery are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, the technique could reduce postoperative ovarian and pelvic adhesions, lowering pain, need for repeat surgery, and adhesion-related fertility problems.
How similar studies have performed: Small prior studies and case series have suggested temporary ovarian suspension may reduce adhesion formation, but randomized and long-term data are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with moderate to severe endometriosis with suspected adhesions, lesions in the ovary, ovarian fossa, utero-sacral ligaments, pouch of douglas, or involvement of the intestine as seen in preoperative assessment who are willing to participate in the study including postoperative follow-up assessments. Exclusion Criteria: * Patients who are not intended to have an endometriosis operation. Patients with minimal to mild endometriosis and no suspected adhesions or ovarian, ovarian fossa, utero-sacral ligament, pouch of douglas involvement on preoperative assessment.
Where this trial is running
Haifa
- Carmel Medical Center — Haifa, Israel (Recruiting)
Study contacts
- Study coordinator: Yuval Kaufman, MD
- Email: mdykaufman@gmail.com
- Phone: +97248250336
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.