Telemedicine therapy for PTSD in people with opioid use disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates a novel telemedicine-delivered prolonged exposure therapy aimed at improving attendance and reducing PTSD symptoms in individuals with opioid use disorder (OUD) who also have PTSD. Participants will be randomly assigned to one of three groups: treatment as usual, prolonged exposure therapy, or prolonged exposure therapy with financial incentives for attendance. The study will involve remote assessments of PTSD symptoms and psychosocial functioning over a 12-week intervention period, followed by follow-up assessments at 3 and 6 months. The goal is to address the high prevalence of PTSD among those with OUD and improve treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \>18 years old
* Maintained on a stable methadone or buprenorphine dose for \>1 month prior to the study
* Meet current DSM-5 posttraumatic stress disorder criteria based on the Clinician Administered PTSD Scale for DSM-5
* Participants receiving psychotropic medications must be maintained on a stable dose for \>1 month prior to enrollment.

Exclusion Criteria:

* Current delusions or hallucinations, unstable bipolar disorder, imminent risk for suicide as assessed by the Mini International Neuropsychiatric Interview
* Cognitive impairment as evidenced by scores \<22 on the Videoconference-based Mini Mental Status Examination (MMSE; Folstein, et al., 1975)
* Enrolled in another ongoing evidence-based treatment for PTSD.
* Pregnancy as verified by pregnancy test
* No access to cellular service

Where it's running

• University of Vemont
  Burlington, Vermont, United States Recruiting

Study contacts

• Study coordinator: Kelly Peck, Ph.D.
• Email: Kelly.Peck@uvm.edu
• Phone: 8026569610

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.