Telemedicine motivational support for heart failure and sleep apnea patients

Effect of Post-Discharge Telemedicine Motivational Enhancement Intervention in Heart Failure and Obstructive Sleep Apnea on Adherence and Health Outcomes

Not applicable Interventional The Cleveland Clinic · NCT04752462

This study is testing if a special telemedicine support program can help people with heart failure and sleep apnea do better than just regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years and up
SexAll
SponsorThe Cleveland Clinic Academic / other
Locations1 site (Cleveland, Ohio)
Trial IDNCT04752462 on ClinicalTrials.gov

What this trial studies

This clinical trial examines the effectiveness of an early intensive telemedicine motivational enhancement program compared to standard care for patients with acute decompensated heart failure (ADHF) and newly diagnosed obstructive sleep apnea (OSA). Participants will receive Auto-CPAP therapy and will be monitored for adherence and patient-reported outcomes over a 6-month period. The study aims to assess the impact of this intervention on hospital readmissions and overall continuity of care. A total of 80 patients will be randomized into two groups to evaluate these outcomes.

Who should consider this trial

Good fit: Ideal candidates are patients admitted with acute decompensated heart failure who have a new diagnosis of obstructive sleep apnea and are treatment-naive to PAP therapy.

Not a fit: Patients who have previously undergone PAP therapy or have significant cognitive dysfunction may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve adherence to CPAP therapy and reduce hospital readmissions for patients with heart failure and sleep apnea.

How similar studies have performed: Other studies have shown promising results with telemedicine interventions for chronic conditions, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Admitting ADHF diagnosis
* OSA diagnosis (REI ≥5)
* Treatment-naive and agreeable to PAP therapy
* Agrees to participate.

Exclusion Criteria:

* Prior or current PAP therapy
* Unable to provide informed consent
* Moderately hypoxic (oxygen saturation \< 87% on room air or requiring \>2L of O2 during overnight sleep study
* Hemodynamically unstable (systolic blood pressure, SBP\<90 mmHg, heart rate\>120bpm)
* Central predominant apnea (Central Apnea Index \> 50% of the Apnea Index) Dementia/cognitive dysfunction
* Unable to participant in video televisits.

Where this trial is running

Cleveland, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute Decompensated Heart FailureObstructive Sleep ApneaMotivational EnhancementPAP Adherence
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.