Telehealth versus in-person follow-up for buprenorphine after an emergency department visit

In Person vs Telehealth Opioid Use Disorder Treatment After Patients Leave the Emergency Department

Not applicable Interventional University of California, Davis · NCT06961058

This project will test whether arranging follow-up buprenorphine care by telehealth or by in-person clinics leads to better long-term treatment retention and patient experience for adults with opioid use disorder who start buprenorphine in the emergency department.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment528 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of California, Davis Academic / other
Locations3 sites (El Centro, California and 2 other locations)
Trial IDNCT06961058 on ClinicalTrials.gov

What this trial studies

Adults who receive buprenorphine for opioid use disorder in one of three emergency departments will be referred to outpatient buprenorphine care either via telehealth (video/phone) or at an in-person clinic. Researchers will track whether patients successfully establish outpatient treatment, how long they remain on buprenorphine, and measures of patient experience over 1, 3, 6, and 9 months. Participants complete baseline and follow-up questionnaires and linkage to outpatient care is monitored. The study aims to compare the two referral approaches to understand which better supports long-term buprenorphine use after ED-initiated treatment.

Who should consider this trial

Good fit: Adults who receive buprenorphine in the emergency department, do not already have an outpatient buprenorphine clinic, can consent, and can complete follow-up in English or Spanish are ideal candidates.

Not a fit: Patients already connected to an outpatient buprenorphine program, those living in institutions, or those unable to consent or complete follow-up in English or Spanish are unlikely to benefit from this referral comparison.

Why it matters

Potential benefit: If successful, this approach could increase long-term buprenorphine retention and reduce overdose risk by making outpatient care easier to access and stay in.

How similar studies have performed: Emergency-department initiation of buprenorphine is evidence-based and telehealth OUD treatment expanded after COVID-19 with promising access and retention results, but direct long-term comparisons of telehealth versus in-person referrals remain limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients who present to the emergency department and receive buprenorphine (either administered or prescribed) to treat OUD
* do not have an established outpatient clinic where they will get buprenorphine when they leave the emergency department

Exclusion Criteria:

* inability to give consent
* patients living in institutions (e.g., nursing homes, prisons)
* unable to complete questionnaires in either English or Spanish

Where this trial is running

El Centro, California and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid Use Disorderemergency departmentbuprenorphinetelehealthcomparative effectiveness
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.