Tele-exercise program for cancer patients
Remote Resistance Exercise Powering Survivors - Gastrointestinal Oncology (Remote REPS - GI)
This study tests a remote exercise program for cancer patients undergoing chemotherapy to see if it helps them feel stronger and better during treatment.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | H. Lee Moffitt Cancer Center and Research Institute Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Tampa, Florida) |
| Trial ID | NCT05664178 on ClinicalTrials.gov |
What this trial studies
This study evaluates a tele-resistance training exercise program designed for individuals undergoing chemotherapy for advanced upper gastrointestinal cancer. Participants will engage in remote exercise sessions aimed at improving their physical strength and overall well-being during treatment. The program targets patients with stage III and IV gastrointestinal cancer, utilizing a structured exercise regimen to enhance recovery and quality of life. The study will assess the feasibility and effectiveness of this approach in a clinical setting.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with biopsy-proven stage III or IV upper gastrointestinal cancer who are undergoing chemotherapy.
Not a fit: Patients who are regularly engaged in resistance training or have significant underlying health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could improve physical strength and quality of life for patients undergoing chemotherapy for gastrointestinal cancer.
How similar studies have performed: Other studies have shown positive outcomes with exercise interventions in cancer care, suggesting potential success for this tele-exercise approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Biopsy-proven upper GI cancer, stage III-IV * ECOG performance status 0-1 * Treatment plan of chemotherapy with planned return to Moffitt Cancer Center for restaging * Able to read and speak English fluently * Capable of providing informed consent Exclusion Criteria: * Regular engagement in RT (2x/week targeting all major muscle groups) * Screen failure for exercise safety based on Physical Activity Readiness Questionnaire (PAR-Q) and Patient-Reported Measurement Information System (PROMIS) screening questions * Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease (New York Heart Association functional class III or IV). * Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT * Numeric pain rating scale of ≥ 7 out of 10 * Myopathic or rheumatologic disease that impacts physical function
Where this trial is running
Tampa, Florida
- Moffitt Cancer Center — Tampa, Florida, United States (Recruiting)
Study contacts
- Principal investigator: Nathan Parker, PhD, MPH — Moffitt Cancer Center
- Study coordinator: Nathan Parker, PhD, MPH
- Email: Nathan.Parker@moffitt.org
- Phone: 813-745-0527
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.