Targeted water, sanitation, and hygiene intervention for cholera prevention
Official title: Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)
Run by Johns Hopkins Bloomberg School of Public Health · NCT06003816 · Data updated 2026-11-12
This study is testing a new water, sanitation, and hygiene program to see if it can help people living near cholera patients stay healthy and reduce infections.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 3140 (estimated) |
| Sponsor | Johns Hopkins Bloomberg School of Public Health Academic / other |
| Locations | 2 sites (Dhaka and 1 other locations) |
| Status | Recruiting |
| Started | October 18, 2023 |
| Main results expected | November 30, 2027 |
| Study ends | November 30, 2027 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT06003816 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals living within close proximity to cholera patients who lack running water in their homes.
✕Probably not a fit
Patients who have access to running water or do not live near cholera cases may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of a targeted water, sanitation, and hygiene (WASH) intervention designed for individuals living near cholera patients. The intervention, known as CHoBI7, will be implemented in cholera transmission hotspots to reduce infections and promote sustained WASH behaviors. The study will involve randomized controlled trials to assess the impact of the intervention on cholera infection rates and hygiene practices among participants. The research builds on previous findings that highlighted the increased risk of cholera for those living close to infected individuals.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce cholera infections and improve hygiene practices in vulnerable populations.
How similar studies have gone: Previous studies have shown success with similar WASH interventions, particularly the CHoBI7 intervention, which effectively reduced cholera rates in patient households.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Index cholera patient have no running water inside of their home Exclusion Criteria: * No one will be excluded because of age, sex, religion, or sexual preference
Where it's running
-
International Centre for Diarrhoeal Disease Research, Bangladesh
Dhaka, Bangladesh Recruiting -
Research Training and Management International
Dhaka, Bangladesh Recruiting
Study contacts
- Principal investigator: Christine Marie George, PhD — Johns Hopkins Bloomberg School of Public Health
- Study coordinator: Christine Marie George, PhD
- Email: cmgeorge@jhu.edu
- Phone: (202) 657-5798
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Gut health follow-along with Peachbiotic in adults
This single-arm study tests whether Peachbiotic taken daily for 12 weeks helps adults with gut symptoms feel better.
-
Impact of a climate-resilient WASH package in Karamoja schools
This study tests a climate-resilient water, sanitation and hygiene package in severely water-insecure primary schools in Karamoja to see if it reduces diarrhea and respiratory infections and improves attendance, especially among girls.
-
Do home water filters improve health for people with private wells in rural Central Appalachia
This study tests whether providing point-of-use water filters to households using well or spring water in rural Central Appalachia can reduce acute gastrointestinal illness.
-
Cholera control around a case area using targeted vaccination (CATI) in Dhaka
This study tests whether vaccinating household contacts around a cholera case in Dhaka can reduce transmission of the disease.
-
Balanced IV Fluids for Kids with Acute Gastroenteritis
This study compares balanced crystalloids versus normal saline for IV hydration in young children with acute gastroenteritis to see if it improves acid–base status and clinical outcomes.
-
Brenipatide (LY3537031) treatment for adults with IBS‑D
This will test whether brenipatide (LY3537031) given under the skin helps adults with IBS‑D reduce belly pain and improve stool consistency compared with placebo.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.